Search for dissertations about: "TIRF"

Showing result 16 - 20 of 20 swedish dissertations containing the word TIRF.

  2. 16. Supported Lipid Membranes and Their Use for the Characterization of Biological Nanoparticles

    Author : Silver Jõemetsa; Chalmers tekniska högskola; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; fluorescence microscopy; supported lipid bilayer; lipophilic dyes; size determination; diffusion; microfluidics;

    Abstract : Biological nanoparticles (BNPs) are nano-sized lipid vesicles of biological origin, which are involved in multiple biological processes. BNP characterization techniques are critical for improving the understanding of how these particles contribute to cellular communication, viral infections and drug-delivery applications. READ MORE

  4. 17. Mechanisms of Integrin Signal Transduction

    Author : Anne Stefansson; Staffan Johansson; Annika Armulik; Björn Öbrink; Uppsala universitet; []
    Keywords : Cell biology; Integrin; Integrin signalling; PI3K; Akt PKB; Integrin transmembrane domain; cell spreading; Cellbiologi;

    Abstract : Integrins are a protein family of cell surface receptors, expressed in all cell types in the human body, except the red blood cells. Besides their importance in mediating physical connections with the surrounding environment, the integrin family members are also vital signalling mediators. READ MORE

  5. 18. Fabrication, development and characterization of a waveguide microscopy device for biological applications

    Author : Mokhtar Mapar; Chalmers tekniska högskola; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; NATURVETENSKAP; NATURAL SCIENCES; Image processing; Lipid bilayer; Waveguide scattering microscopy; Waveguide fluorescent microscopy; Virus; Nanofabrication;

    Abstract : Our understanding of biological systems has advanced significantly thanks to the development of microscopy methods and suitable biological assays. Surface based methods have increasingly gained interest thanks to their superior sensitivity and ease of use. READ MORE

  6. 19. Architecture and function of the insulin granule secretion machinery

    Author : Peng Yin; Sebastian Barg; Herbert Gaisano; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Docking; Syntaxin-1A; Voltage-gated Ca2 Channels; Exocytosis; Type-2 Diabetes;

    Abstract : Insulin is released into the blood stream to normalize elevated blood glucose, for example after a meal. The hormone is synthesized by β-cells in the endocrine pancreas, and stored in small vesicles, known as secretory granules, until required. When glucose is elevated, these granules undergo regulated exocytosis and thereby secrete the hormone. READ MORE

  7. 20. Non-coding RNAs in beta cell insulin secretion - emerging players in Type 2 Diabetes pathogenesis

    Author : Jones Ofori; Diabetes - öcellsexocytos; []
    Keywords : T2D; insulin secretion; exocytosis; ncRNAs; GAS5; miR-152; miR-335; miR-130a b; miR-375; STXBP1; SNAP25; SYT13; PDHA1; PDX1; glucocortiocoid; beta cell function; glucose metabolism;

    Abstract : Type 2 diabetes (T2D) is a complex polygenic disease influenced by both environmental and genetic factors resulting in impaired insulin release from pancreatic beta cells and insulin resistance in target tissues. The incidence of T2D is escalating and it is projected that over 640 million people will be affected by 2040. READ MORE