Search for dissertations about: "TIRF"
Showing result 6 - 10 of 20 swedish dissertations containing the word TIRF.
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6. Assay development for studies of G protein-coupled receptors at the single-molecule level
Abstract : G protein-coupled receptors (GPCRs), also known as seven transmembrane (7TM) receptors,is the largest family of cell surface receptors. These receptors play a key role in transmittinga wide variety of signals across the cell membrane and are involved in physiologicalprocesses such as sensory transduction, cell-cell communication, neuronal transmission,and hormonal signaling. READ MORE
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7. Development of novel bioanalytical assays with single-molecule readout for biomarker detection and drug candidate characterization
Abstract : Bioanalytical assays with single-molecule readout for studying molecular interactions have in the past decades received increasing attention. The high sensitivity often offered by this readout scheme has for example enabled ultra-sensitive analyte detection, having important implications for monitoring early disease progression and the effects of drug treatment. READ MORE
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8. Binding Kinetics of Proteins at Immune-Cell Contacts
Abstract : Protein-protein interactions are crucial in numerous cellular functions and biological processes that take place inside our body. It is therefore not surprising that these interactions also govern the response of our body´s defence mechanism, the so-called immune system, towards an infection. READ MORE
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9. The influence of adhesion molecules on binding and protein organization in cell contacts
Abstract : Interactions between immune cells such as T cells and antigen-presenting cells (APCs) are integral for mounting an adaptive immune response. The interaction between the T cell receptor (TCR) and the antigen-presenting major histocompatibility complex (pMHC) on a contacting T cell and APC, is widely accepted to be the key interaction. READ MORE
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10. Towards the Characterization of Biological Nanoparticles
Abstract : .... READ MORE