Search for dissertations about: "TLR2 1"

Showing result 11 - 15 of 36 swedish dissertations containing the words TLR2 1.

  2. 11. Signaling and Adhesive Mechanisms in Acute Pancreatitis

    Author : Darbaz Awla; Kirurgi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; trypsinogen activation; Acute pancreatitis; leukocyte recruitment and adhesion;

    Abstract : Acute pancreatitis (AP) is an inflammatory disease with variable severity ranging from mild interstitial edematous to severe necrotizing disease. The overall mortality rate of AP is 8-9%. Specific treatment of AP is lacking which is partly related to an incomplete understanding of the basic pathophysiology behind the disease. READ MORE

  4. 12. Innate and adaptive immune responses in the lungs. Contribution to protection against mycobacterial infections

    Author : Olga Daniela Chuquimia Flores; Carmen Fernández; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES;

    Abstract : Host defense against Mycobacterium tuberculosis (Mtb) is mediated by a combination of innate and adaptive immunity. In this thesis we investigated the role of components of innate system such as TLR2 signalling and alveolar epithelial cells type II (AEC II) in the immune responses against mycobacterial infections. READ MORE

  5. 13. Intracellular regulation of TLR signaling Basic mechanisms and importance in intestinal inflammation

    Author : Martin Berglund; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; TLR IL-1R signalling; Gαi2- - mice; IRAK; peritoneal macrophages; cross-tolerance; dextran sulfate sodium; IBD;

    Abstract : Toll-like receptors (TLRs) recognize conserved structures on/in microorganisms. The intracellular signalling pathways of TLRs are shared with IL-1R and IL-18R and their activation leads to transcription of proinflammatory cytokines and type-I interferons. READ MORE

  6. 14. Preterm and term cervical ripening : studies on CRH, HMGB1, toll-like receptors, cytokines and matrix metalloproteinases

    Author : Aurelija Dubicke; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Cervical fibroblasts; cervical ripening; cervix; chemokines; cytokines; CRH; HMGB1; interleukin; labor; preterm; preterm labor; matrix metalloproteinases; pregnancy; PPROM; Tolllike receptors;

    Abstract : Objective: Preterm birth (PTB) is the leading cause of neonatal mortality and morbidity. Despite the existing treatment, the frequency of PTB has not changed in the past thirty years. Incomplete understanding of the biological and pathophysiological mechanisms underlying preterm delivery is the major obstacle to preventing PTB. READ MORE

  7. 15. Molecular mechanisms in idiopathic inflammatory myopathies

    Author : Mei Zong; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Background: Myositis is a group of rare autoimmune diseases. Muscle weakness and fatigue are the dominant symptoms and inflammation with T cells and macrophages is a characteristic finding in muscle tissue. READ MORE