Search for dissertations about: "TLR3"

Showing result 1 - 5 of 35 swedish dissertations containing the word TLR3.

  2. 1. Effects of the host defense peptide LL-37 on human cells : Immunomodulation and cytotoxicity

    Author : Sara Bodahl; Kärlfysiologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; LL-37; Host defense peptides; Cathelicidin; Inflammation; Cytotoxicity; TLR3; Poly I:C;

    Abstract : The human host defense peptide LL-37 has an essential role in the first line of defense against invading pathogens. This cathelicidin is mainly produced by immune cells and epithelial cells aligning the mucosal areas and is normally upregulated upon infection and inflammation. READ MORE

  4. 2. Arthritogenecity of RNA and its degradation products

    Author : Fariba Zare; Göteborgs universitet; []
    Keywords : dsRNA; ssRNA; virus; arthritis; TLR3; IL-1R; IFNalpha beta receptor; plasminogen; tissue factor; uric acid; inflammation; arthritis; neutrophils;

    Abstract : Viral infections often lead to arthralgias and overt arthritic states. Expression of double stranded RNA (dsRNA) is a common feature of all viruses during their replication and it has been suggested that it is able to induce production of pro-inflammatory cytokines, e.g., interferon-alpha (IFN-alpha). READ MORE

  5. 3. Requirements for the Induction of Adaptive Immune Responses to Rotavirus

    Author : Joy Nakawesi; Virusrekognition; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Rotavirus; classical dendritic cells; Lymphoid organ hypertrophy; B cells; IgA; Retinoic acid; CD8 T cells; TLR3 and Poly I:C ;

    Abstract : Rotavirus (RV) infections remain the leading cause of world-wide diarrhea-associated morbidity and mortality among children 200,000 deaths annually mostly in the low-income countries of Africa and Asia. Efficient clearance of the primary RV infection and protection from future re-infections is mediated by adaptive immune responses. READ MORE

  6. 4. Toll-like Receptors in Allergic Rhinitis

    Author : Mattias Fransson; Malmö Institutionen för kliniska vetenskaper; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; neutrophils; poly I:C ; uteroglobin; Toll-like receptors; Medicine human and vertebrates ; Medicin människa och djur ; Otorhinolaryngology; audiology; auditive system and speech; Otorinolaryngologi; audiologi; hörsel- och talorganen; innate immunity; LPS; allergic rhinitis; bone marrow;

    Abstract : Allergic rhinitis is an inflammatory disorder with the characteristic symptoms itching, sneezing, secretion and blockage upon allergen contact. In addition to the local inflammation in the nose, there is a systemic component that influences peripheral blood, bone marrow and lungs. READ MORE

  7. 5. Emerging role of RIG-I-like receptors in antiviral innate immunity in airway structural cells

    Author : Jenny Calvén; Respiratorisk immunofarmakologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Abstract : Respiratory viral infections, especially involving rhinovirus, are main triggers of exacerbations of asthma and COPD. These severe conditions are a great burden to both the individual and society and currently lack effective treatments. READ MORE