Search for dissertations about: "TMAs"

Showing result 6 - 9 of 9 swedish dissertations containing the word TMAs.

  2. 6. Immunohistochemical and molecular studies on ovarian cancer progression and prognosis

    Author : Björn Nodin; Tumörmikromiljö; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Epithelial ovarian cancer; prognostic and predictive biomarkers; tissue microarrays; androgen receptor; RBM3; Chek1; Chek2; MCM3; Dachshund 2; SATB1; KRAS mutation;

    Abstract : Epithelial ovarian cancer (EOC) is the most lethal malignancy of the female reproductive tract. Due to vague symptomatology, the majority of EOC patients are diagnosed in advanced clinical stages with poor survival rates, despite improvements in surgical techniques and the advent of targeted therapeutics. READ MORE

  4. 7. Breast cancer in young women : aspects on mortality and local recurrence

    Author : Hanna Fredholm; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : The general aim of the thesis was to gain increased insight into the long-term prognosis for young women with breast cancer. In a population-based cohort of 22,017 women with breast cancer, we studied prognosis by age. Women aged .. READ MORE

  5. 8. The use of immunological biomarkers to improve individualization of postoperative radiotherapy in breast cancer

    Author : Axel Stenmark Tullberg; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Tumor-infiltrating lymphocytes; CD8; FOXP3; Radiotherapy; Breast cancer;

    Abstract : Radiotherapy (RT) forms the cornerstone of most curative breast cancer treatment due to its well-established risk-reducing effect on local recurrences at the population level. However, there is heterogeneity regarding treatment benefits at the individual level, and research currently aims to better tailor treatment decisions based on tumor biology. READ MORE

  6. 9. Targeting stromal components in the tumor microenvironment for cancer therapy

    Author : Jieyu Wu; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : In the tumor microenvironment (TME), different cell components crosstalk with each other through various growth factors, cytokines, chemokines, and enzymes. They offered crucial survival signals for tumor cell proliferation and metastasis. READ MORE