Search for dissertations about: "TME"
Showing result 1 - 5 of 37 swedish dissertations containing the word TME.
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1. Rectal cancer surgery : Defunctioning stoma, anastomotic leakage and postoperative monitoring
Abstract : The understanding of the mesorectal spread in rectal cancer has lead to wide acceptance of total mesorectal excision (TME) as the surgical technique of choice for carcinoma in the lower and mid rectum. While oncological results and survival have improved with TME-surgery, morbidity and mortality remain important issues. READ MORE
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2. The identification and functional evaluation of novel cancer-associated fibroblast subtypes and matrisome proteins in pancreatic cancer
Abstract : Pancreatic ductal adenocarcinoma (PDAC) is a highly lethal malignancy characterized by an extensive desmoplastic stroma. The stroma is the site of intricate communication between malignant cells and their surrounding environment. READ MORE
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3. Immunologic Markers in the Tumor Microenvironment of Classical Hodgkin Lymphoma
Abstract : In classical Hodgkin lymphoma (cHL), cytokine regulation and cellular composition of the tumor microenvironment (TME) is crucial for tumor cell survival. In paper I, we examined the presence of CD138+ plasma cells and IgG4+ plasma cells in diagnostic cHL biopsies with immunohistochemistry (IHC). READ MORE
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4. Rectal cancer : staging, radiotherapy and surgery
Abstract : In Sweden, about 1800 patients are annually diagnosed with adenocarcinoma of the rectum. Surgery remains the major primary treatment. Adjuvant radiotherapy and total mesorectal excision (TME) are two major achievements in rectal cancer treatment during the last two decades. READ MORE
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5. Art of tumor immunity : extricating hypoxia-driven immunosuppression in the solid tumor microenvironment
Abstract : The fate of tumors, from initiation to in situ carcinoma and ultimately metastasis, is intricately tied to the balance between the immune system’s effector cytotoxic and tolerogenic immunosuppressive responses, collectively known as tumor immunity. However, this balance is disrupted by hypoxia, a common characteristic of solid tumors, which drives immunosuppression and contributes to the heterogeneity of the solid tumor microenvironment (TME). READ MORE