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Showing result 1 - 5 of 202 swedish dissertations matching the above criteria.

  2. 1. TNF-α and neurotrophins in Achilles tendinosis

    Author : Johan Bagge; Sture Forsgren; Tomas Movin; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Achilles tendon; tendinosis; tendinopathy; neurotrophins; TNF-alpha; physical acitivity; apoptosis; proliferation; pain; remodelling; anatomi; Human Anatomy;

    Abstract : Tenocytes are the principal cells of the human Achilles tendon. In tendinosis, changes in the metabolism and morphology of these cells occur. Neurotrophins are growth factors essential for the development of the nervous system. READ MORE

  4. 2. Inflammatory Reactions in Peritonitis and Malignant Obstructive Jaundice : Clinical and Experimental Studies with Special Emphasis on the Cellular Immune Response

    Author : Johanna Österberg; Ulf Haglund; Mikael Ljungdahl; Roland Andersson; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Surgery; CLP; sepsis; peritonitis; bacterial translocation; malignant obstructive jaundice; Linomide; COX inhibitor; SC-236; indometacin; T lymphocyte; macrophage; mucosa; MLN; gut immune cell distribution; mucosal injury; cytokines; TNF-α; IL-6; IL-10; endotoxin; caspase-3; apoptosis; Kirurgi; Surgery; Kirurgi;

    Abstract : Patients with peritonitis or malignant obstructive jaundice (HPB+) have an increased morbidity and mortality due to sepsis. An altered cell-mediated immunity in the intestinal mucosa might promote gut barrier failure, increased endotoxin and cytokine release and bacterial translocation (BT) in these conditions. READ MORE

  5. 3. Oxidative Stress, Angiogenesis and Inflammation in Normal Pregnancy and Postpartum

    Author : Maria Palm; Ove Axelsson; Samar Basu; Charlotta Grunewald; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Angiogenesis; inflammation; IL-6; F2-isoprostanes; oxidative stress; Pentraxin 3; PGF2α; PlGF; pregnancy; sFlt1; TNF-α; VEGF-A; Obstetrik och gynekologi; Obstetrics and Gynaecology; Medicinsk vetenskap; Medical Science;

    Abstract : The aims were to investigate oxidative stress (I), angiogenesis (II) and inflammation (III-IV) in healthy women during pregnancy and postpartum. Oxidative stress was estimated by measurement of 8-iso-PGF2α and the antioxidants α- and γ-tocopherol. READ MORE

  6. 4. Adult Neural Stem Cells-Influence of Stroke, Inflammation and Aging

    Author : Henrik Ahlenius; Lund Neurologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; inflammation; Neural stem cells; adult; neurogenesis; stroke; aging; TNF-R1; TNF-α;

    Abstract : Neural stem cells (NSCs) in the embryo generate neurons, astrocytes and oligodendrocytes, the principal cells of the central nervous system (CNS), which contribute to the full diversity of the brain. Some NSCs persist in the adult brain and ensures neurogenesis throughout adult life in the subventricular zone (SVZ) and the subgranular zone (SGZ). READ MORE

  7. 5. Development of a New Biomechanical ex vivo Perfusion System - Studies on effects of biomechanical and inflammatory stress on hemostatic genes in human vascular endothelium

    Author : Niklas Bergh; Göteborgs universitet; []
    Keywords : ex vivo perfusion system; biomechanical; endothelium; shear stress; tensile stress; pulsatile; TNF-α; JNK; hemostatic genes;

    Abstract : The vascular endothelium is a multifunctional interface constantly exposed to biomechanical forces such as shear and tensile stress. Biomechanical stress is involved in the pathophysiological process of the vessel wall and thus affects vascular remodeling, atherosclerosis and thrombogenesis. READ MORE