Search for dissertations about: "TNFalpha."

Showing result 1 - 5 of 40 swedish dissertations containing the word TNFalpha..

2. 1. Effects of cytokines on preadipocyte differentiation and Wnt signalling

   Author : Birgit Gustafson; Göteborgs universitet; []
   Keywords : adipocyte differentiation; adiponectin; beta-Catenin; C EBPalpha; IL-6; PPARgamma; TNFalpha; Wnt signalling;

   Abstract : The relationship between amount of adipose tissue, the Metabolic Syndrome and Type 2 diabetes has been recognized for several years. However, the mechanisms for this remain to be clarified. Not all obese individuals develop insulin resistance or Type 2 diabetes and these perturbations are also seen in non-obese individuals. READ MORE

4. 2. TNFalpha expression in monocytes/macrophages

   Author : Karolina Andersson; Institutionen för experimentell medicinsk vetenskap; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Biomedicinska vetenskaper allmänt ; General biomedical sciences; Protein kinase; Macrophage; TNF;

   Abstract : The recognition of microbes or microbial products by leukocytes is a key event in innate immunity. Binding of microbial products to cell surface receptors on phagocytes induce a response that includes the production of inflammatory mediators. One such mediator is the cytokine tumour necrosis factor alpha (TNF). READ MORE

5. 3. Diabetic Vascular Complications & Inflammation - role of NFAT and TNFalpha

   Author : Jenny Öhman; Kardiovaskulär forskning - immunitet och ateroskleros; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; vascular; hyperglycemia; osteopontin; NFAT; diabetes; retinopathy; TNF; UTP;

   Abstract : Vascular complications of diabetes account for the majority of morbidity and mortality among diabetic patients. Large clinical trials have identified hyperglycemia as a risk factor in the development of diabetic vascular complications. READ MORE

6. 4. Adult neural stem cells in neuroinflammation

   Author : Ruxandra Covacu; Karolinska Institutet; Karolinska Institutet; []
   Keywords : Neural stem cells; inflammation; EAE; NO; neurogenesis; HMGB1; TLR; TNFalpha;

   Abstract : Adult neural stem cells (NSC) can be isolated from the subventricular zone (SVZ) of the lateral ventricles, the subgranular zone (SGZ) of the hippocampus and the central canal of the spinal cord. These cells are thought to have regenerative potential and pose important therapeutic possibilities in neuroinflammatory conditions such as Multiple Sclerosis (MS). READ MORE

7. 5. Invasion promoting factors in endometriotic and endometrial tissue

   Author : Christina Bruse; Karolinska Institutet; Karolinska Institutet; []
   Keywords : Endometriosis; endometrium; PF; tPA; uPA; uPAR; PAI-1; PAI-2; IL-1beta; IL-6; TNFalpha.;

   Abstract : Endometriosis is a common gynaecologic disorder, affecting women of fertile age with pelvic pain and infertility, and is characterized by the presence of endometrial glands and stroma outside the uterine cavity. Retrograde shed endometrial fragments are presumed to adhere to pelvic structures and grow invasively, thereby creating endometriotic tissue. READ MORE