Search for dissertations about: "TOMA"

Showing result 1 - 5 of 21 swedish dissertations containing the word TOMA.

  2. 1. Regulatory roles for long noncoding RNAs and circular RNAs in human skin wound repair

    Author : Maria-Alexandra Toma; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Human skin wound repair is a multiphase process, which includes inflammation, growth and remodeling, and requires the concerted communication of many cell types. During the course of healing, skin cells find themselves in a hostile environment where processes like migration, differentiation, apoptosis and proliferation must be correctly executed in order to restore the integrity of the injured tissue. READ MORE

  4. 2. Theoretical modelling of tumour oxygenation and influences on treatment outcome

    Author : Iuliana Toma-Dasu; Mikael Karlsson; Svensson Hans; J F Fowler; Borivoj Vojnovic; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Radiation sciences; Computer simulation; Electrode; Polarographic measurements; Tumour oxygenation; Hypoxia; Strålningsvetenskap; Radiation biology; Strålningsbiologi; radiofysik; radiation physics;

    Abstract : One of the main problems in curing cancer resides in the different microenvironment existing in tumours compared to the normal tissues. The mechanisms of failure are different for radiotherapy and chemotherapy, but they all relate to the poor blood supply known to exist in tumours. READ MORE

  5. 3. Advanced Machine Learning Methods for Oncological Image Analysis

    Author : Mehdi Astaraki; Chunliang Wang; Örjan Smedby; Iuliana Toma-Dasu; Bjoern Menze; KTH; Karolinska Institutet; Karolinska Institutet; []
    Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Medical Image Analysis; Machine Learning; Deep Learning; Survival Analysis; Early Response Assessment; Tumor Classification; Tumor Segmentation; Medicinsk teknologi; Medical Technology;

    Abstract : Cancer is a major public health problem, accounting for an estimated 10 million deaths worldwide in 2020 alone. Rapid advances in the field of image acquisition and hardware development over the past three decades have resulted in the development of modern medical imaging modalities that can capture high-resolution anatomical, physiological, functional, and metabolic quantitative information from cancerous organs. READ MORE

  6. 4. Optimization of brachytherapy for cervical cancer using inverse planning algorithms

    Author : Lucilio dos Santos Matias; Iuliana Toma-Dasu; Brígida da Costa Ferreira; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Brachytherapy; treatment planning optimization; IPSA; HIPO; radiobiology; complicationfree; medicinsk strålningsfysik; Medical Radiation Physics;

    Abstract : Carcinoma of the cervix is a global problem. Brachytherapy (BT) is one of the mainradiation therapy components used in the management of cervical cancer. READ MORE

  7. 5. A Novel Approach for Radiotherapy and Radiosurgery Treatment Planning Accounting for High-Grade Glioma Invasiveness into Normal Tissue

    Author : Wille Häger; Iuliana Toma-Daşu; Marta Lazzeroni; Jesper Kallehauge; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Tumor modeling; medical physics; model; simulation; glioblastoma; gbm; medicinsk strålningsfysik; Medical Radiation Physics;

    Abstract : High-grade gliomas (HGGs) are a type of malignant brain cancer, which include glioblastomas (GBMs). In adults, GBM is the most common malignant primary brain cancer. Attempts to treat patients with GBMs have been conducted for over a century, but the prognosis has only marginally improved. READ MORE