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Found 3 swedish dissertations matching the above criteria.
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1. Microglial cells in Neurodegenerative Diseases. The Role of Galectin-3
Abstract : Today, dementia such as, Alzheimer’s disease (AD), vascular diseases and motor neurodegenerative diseases, such as Parkinson’s disease (PD), represent a major public health problem. For instance, PD affect to more than 10 million people worldwide and almost 50 million people are affected by dementia. READ MORE
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2. Preclinical PET imaging and therapy of Alzheimer's disease
Abstract : The main histopathological hallmarks of Alzheimer’s disease are extracellular amyloid-beta (Aβ) plaques and intracellular neurofibrillary tangles, containing tau protein. Because of misfolded and aggregated proteins, activated microglia and astroglia react with a neuroinflammatory response, which may contribute to disease progression and severity. READ MORE
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3. Identifying and targeting vulnerabilities in cancers that metastasize to the bone and bone marrow
Abstract : Evolving technologies enable scientist to ask and seek answers to advanced questions, above and beyond. During the past decade single-cell RNA sequencing (scRNA-seq) has revolutionized our understanding of biology, in particular within cancer research. READ MORE