Search for dissertations about: "TWINKLE"

Showing result 1 - 5 of 10 swedish dissertations containing the word TWINKLE.

  2. 1. Olfactory genomics of bark- and ambrosia beetles : Evolution and function of chemoreceptors

    Author : Twinkle Biswas; Feromongruppen; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Curculionidae; functional characterisation; odorant receptors ORs ; gustatory receptors; ionotropic receptors; orthologues; paralogues; olfactory sensory neurons; OR-ligand interaction;

    Abstract : Insect behaviours, such as host and mate selection, are often mediated by chemical cues. The chemical cuesare detected by large and rapidly evolving families of chemoreceptors which include odorant receptors (ORs),gustatory receptors (GRs) and ionotropic receptors (IRs). READ MORE

  4. 2. Molecular and structural studies of proteins required for mitochondrial DNA maintenance

    Author : Carlos Pardo-Hernandez; Göteborgs universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; mtDNA; LONP1; POLγ; mtDNA maintenance; mitochondrial disease; TWINKLE; mitochondria;

    Abstract : Mitochondria are membrane-bound organelles that produce the majority of ATP used to drive metabolic processes in eukaryotic cells. A unique feature of mitochondria is the existence of a separate mitochondrial DNA (mtDNA), which codes for thirteen proteins needed for oxidative phosphorylation (OXPHOS). READ MORE

  5. 3. DNA precursor biosynthesis-allosteric regulation and medical applications

    Author : Reza Rofougaran; Anders Hofer; Thomas Borén; Staffan Eriksson; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Biochemistry; DNA biosynthesis; ribonucleotide reductase; allosteric regulation; Trypanosoma brucei; adenosine kinase; nucleoside analogs; mitochondrial DNA; TWINKLE; Biokemi; medicinsk biokemi; Medical Biochemistry;

    Abstract : Ribonucleotide reductase (RNR) is a key enzyme for de novo dNTP biosynthesis. We have studied nucleotide-dependent oligomerization of the allosterically regulated mammalian RNR using a mass spectrometry–related technique called Gas-phase Electrophoretic Mobility Macromolecule Analysis (GEMMA). READ MORE

  6. 4. Molecular mechanisms of mitochondrial DNA replication

    Author : Teresa Holmlund; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Mitochondria; mtDNA; replication; helicase; TWINKLE; POLgamma; POLgammaB; mtSSB; adPEO;

    Abstract : Mitochondria are the energy producing organelles of eukaryotic cells. The organelle has its own genome, the mitochondrial DNA (mtDNA) that encodes 13 subunits of the respiratory chain (RC) complexes, two rRNAs and 22 tRNAs. READ MORE

  7. 5. Functional and structural characterization of the human mitochondrial helicase

    Author : Jenny Korhonen; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Mitochondria; mtDNA; replication; replisome; TWINKLE; mtSSB; POL g ; adPEO.;

    Abstract : Mitochondria are the energy producing organelles of the eukaryotic cell. The human mitochondrial DNA (mtDNA) is a double stranded circular molecule of about 16 kb, usually present at 1000-10 000 copies per cell. The genome encodes 13 polypeptides involved in respiration, two ribosomal RNA s and a set of 22 transfer RNA s. READ MORE