Search for dissertations about: "Tau protein"
Showing result 16 - 20 of 113 swedish dissertations containing the words Tau protein.
-
16. Prion-like Proteins in Neurodegeneration
Abstract : Alzheimers och Parkinsons sjukdom är de vanligaste och näst vanligaste neurodegenerativa sjukdomarna som globalt drabbar ca 30 respektive 6 miljoner människor. I och med vår åldrande befolkning kommer det antalet bara att öka. READ MORE
-
17. Molecular Mechanisms of Frontotemporal Lobar Degeneration
Abstract : The aim of this thesis was to identify genetic factors involved in frontotemporal lobar degeneration (FTLD), a neurodegenerative disorder clinically characterised by a progressive change in personality, behaviour and language. FTLD is a genetically complex disorder and a positive family history is found in up to 40% of the cases. READ MORE
-
18. Protein phosphatases and kinases implicated in Alzheimer's disease abnormal tau phosporylation
Abstract : This thesis describes the distribution, levels and activities of a number of protein kinases and protein phosphatases (PPs) implicated in the abnormal phosphorylation of the tau protein that forms the paired helical filaments (PHFs) of Alzheimer's disease (AD) neurofibrillary tangles (NFTs). Paper I describes the immunocytochemical localization of PP-1, PP-2A, PP-2B and PTP-1B, as well as the protein kinase MAP kinase and p34cdc2 in the hippocampal formation of AD and control brains. READ MORE
-
19. Prognostic subtypes in Parkinson’s disease and related disorders. Clinical, genetical, and biochemical markers for long-term social, motor, and cognitive development
Abstract : .... READ MORE
-
20. Caspase activation in human neuroblastoma cells: mechanisms and spatiotemporal aspects
Abstract : Apoptosis is one of the modes of programmed cell death, in which several members of the caspase family of proteases play the central role. However, activation of apoptotic caspases does not necessarily lead to cell death. READ MORE