Search for dissertations about: "Tau protein"

Showing result 21 - 25 of 113 swedish dissertations containing the words Tau protein.

  2. 21. Amyloid β-protein, Cystatin C and Cathepsin B as Biomarkers of Alzheimer's Disease

    Author : Johan Sundelöf; Lars Lannfelt; Lena Kilander; Hans Basun; Johan Sundstrom; Laura Fratiglioni; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Alzheimer´s disease; amyloid β-protein; cystatin C; cathepsin B; biomarkers; risk factors; epidemiology; Geriatrics and medical gerontology; Geriatrik och medicinsk gerontologi; Medicin; Medicine;

    Abstract : It is suggested that Alzheimer’s disease (AD) is caused by an imbalance between production, degradation and clearance of the amyloid-β (Aβ) protein. This imbalance leads to aggregation of Aβ and tau proteins and neurodegeneration in the brain. READ MORE

  4. 22. On the pathophysiology of idiopathic adult hydrosephalus syndrome : energy metabolism, protein patterns, and intracranial pressure

    Author : Aina Ågren Wilsson; Per Enblad; Umeå universitet; []
    Keywords : hydrocephalus; biochemical markers; microdialysis; cerebrospinal fluid; B waves; brain tissue oxygen tension; Neurology; neurologi;

    Abstract : The symptoms in Idiopathic Adult Hydrocephalus Syndrome (IAHS) – gait disturbance, incontinence, and cognitive deficit – correlate anatomically to neuronal dysfunction in periventricular white matter. The pathophysiology is considered to include a cerebrospinal fluid (CSF) hydrodynamic disturbance, including pressure oscillations (“B waves”), in combination with cerebrovascular disease. READ MORE

  5. 23. Evaluation of amyloid precursor protein and ß-amyloid as biomarkers for Alzheimer s disease

    Author : Annika Olsson; Göteborgs universitet; []
    Keywords : Alzheimer s disease; amyloid precursor protein; ß-amyloid; biomarker; cerebrospinal fluid; enzyme-linked immunosorbent assay; plasma;

    Abstract : Alzheimer s disease (AD) is a neurodegenerative disorder characterised by accumulations of neurofibrillary tangles and amyloid plaques. The major components of the amyloid deposits are the ß-amyloid (Aß) peptides derived from the amyloid precursor protein (APP). READ MORE

  6. 24. Altered proteins in the aging brain

    Author : Adila Elobeid; Irina Alafuzoff; Lena Claesson-Welsh; Thomas Brännström; Uppsala universitet; []
    Keywords : Cognitively unimpaired subjects; Hyperphosphorylated tau; Beta amyloid; Alpha-synclein; Transactive response DNA binding protein 43; Patologi; Pathology;

    Abstract : The classification of neurodegenerative disorders is based on the major component of the protein aggregates in the brain. The most common altered proteins associated with neurodegeneration are Hyperphosphorylated tau (HPt), beta amyloid (Aβ), alpha-synclein (αS) and transactive response DNA binding protein 43 (TDP43). READ MORE

  7. 25. Amyloid precursor protein : cellular studies and animal models

    Author : Tatjana Nilsson; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Alzheimer's disease (AD) is a progressive neurodegenerative disorder characterised by a number of neuropathological features, including extracellular deposits composed primarily of amyloid-β (Aβ) peptides. Aβ is derived from proteolysis of the amyloid precursor protein (APP) by consecutive action of β and γ-secretases. READ MORE