Search for dissertations about: "Tb drugs"

Showing result 1 - 5 of 40 swedish dissertations containing the words Tb drugs.

2. 1. Pharmacokinetic and pharmacogenetic aspects of drug-drug interactions between antiretroviral and anti-tuberculosis drugs in Ethiopian patients : implication for optimization of TB-HIV co-treatment

   Author : Abiy Habtewolde Eyakem; Karolinska Institutet; Karolinska Institutet; []
   Keywords : ;

   Abstract : TB and HIV are immuno-pathologically interacting epidemic infectious diseases affecting the lives of millions globally & sub-Saharan African region accounts the highest burden of both diseases. Although effective therapies are available for the management of each, TB-HIV co-treatment has faced challenges mainly due to drug-drug interactions & overlapping drug toxicities. READ MORE

4. 2. Incidence, predictors and biomarkers for antiretroviral and/or anti-tuberculosis drugs induced liver injury

   Author : Getnet Yimer Ali; Karolinska Institutet; Karolinska Institutet; []
   Keywords : ;

   Abstract : Anti-tuberculosis and/or antiretroviral drugs induced liver injury (DILI) is a major challenge when managing TB and/or HIV patients. The aims of this thesis were to identify incidence, risk factors, and management of DILI among 4 different treatment groups namely; HIV positive individuals with no TB co-infection and had a CD4 count of < 200 cells/μl (taking ARV drugs alone = arm 1), TB-HIV co-infected patients with a CD4 count of < 200 cells/μl (taking both anti-TB and ARV drugs = arm 2), TB-HIV co-infected patients with a CD4 count of > 200 cells/μl (taking anti-TB alone = arm 3), HIV negative TB patients (taking anti-TB alone = arm 4). READ MORE

5. 3. HIV treatment outcomes in Uganda : the impact of baseline characteristics and variability in pharmacokinetics and pharmacogenetics of antiretroviral drugs

   Author : Sarah Nanzigu; Karolinska Institutet; Karolinska Institutet; []
   Keywords : ART Outcomes;

   Abstract : Guidelines specify criteria for initiation and monitoring of antiretroviral treatment (ART), including options for first line regimens. Immunological progress remains a widely used form of HIV/ART monitoring and efavirenz, a preferred first line antiretroviral drug. READ MORE

6. 4. Drug-resistant Mycobacterium tuberculosis in Estonia

   Author : Annika Krüüner; Karolinska Institutet; Karolinska Institutet; []
   Keywords : Tuberculosis; Estonia; M. tuberculosis; drug resistance; MDR-TB; Beijing genotype; cross-resistance; kanamycin; amikacin; rrs mutations; 16S rRNA; exposure; nosocomial transmission; mycobacterial persistence; re-infection; DST; second-line drugs; Bactec; 460; DNA fingerprinting; spoligotyping;

   Abstract : Tuberculosis (TB) infection and disease patterns among different populations are extremely heterogeneous. This thesis explores mainly by microbiological methods the epidemiology of TB in Estonia. Through the work high rates of drug resistance were found. READ MORE

7. 5. Bridging the Gap : implementing tuberculosis and HIV/AIDS collaborative activities in the Northwest Region of Cameroon

   Author : Barnabas N Njozing; Anna-Karin Hurtig; Miguel San Sebastian Chasco; Kerstin E Edin; Pius Muffih Tih; John D Porter; Umeå universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Tuberculosis; HIV AIDS; collaborative activities; Northwest Region; Cameroon.; Public health science; Folkhälsovetenskap; folkhälsa; Public health;

   Abstract : Introduction The human immunodeficiency virus (HIV) epidemic has led to the upsurge of tuberculosis (TB) infection globally, but most especially in areas with high HIV prevalence. In the past, there was lack of a coordinated global and national response between TB and HIV programmes to curb the devastating impacts of both infections. READ MORE