Search for dissertations about: "Telomere dynamics"

Showing result 1 - 5 of 12 swedish dissertations containing the words Telomere dynamics.

  2. 1. What modulates telomere dynamics? : Inheritance, developmental effects, and physiological challenges

    Author : Ye Xiong; MEMEG; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Telomere; Telomere dynamics; Telomere length; telomere inheritance; Zebra finch; Immune challenge; Heritability; Taenopygia guttata; Physiological parameter;

    Abstract : Telomeres are the conservative sequence repeats located at the end of linear chromosomes that have been the focus of intensive research across many disciplines over the last four decades. They function as a cap to protect the chromosome ends from fusion to other chromosomes and to prevent chromosome degradation. READ MORE

  4. 2. Telomere length : dynamics and role as a biological marker in malignancy

    Author : Ulrika Svenson; Göran Roos; Uwe Martens; Umeå universitet; []
    Keywords : Telomere length; peripheral blood; immune cells; breast cancer; renal cell carcinoma; biological marker; patologi; Pathology;

    Abstract : Telomeres are protective structures at the end of our chromosomes, composed of multiple repeats of the DNA sequence TTAGGG. They are essential for maintaining chromosomal stability by preventing damage and degradation of the chromosome ends. READ MORE

  5. 3. The maintenance of telomeres in the budding yeast Naumovozyma castellii

    Author : Humberto Itriago; Molekylär cellbiologi; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Telomere; Telomere dynamics; Telomere-Binding Proteins; Cdc13; Rap1; RAD52; Rad51; Homologous recombination; ALT; Budding yeast; Naumovozyma castellii;

    Abstract : Linear chromosomes of eukaryotic cells require the presence of functional nucleoprotein terminal structures, known as telomeres, to protect the integrity of the genome. The telomere is a highly dynamic and regulated structure constituted by short tandem DNA repeats rich in guanine nucleotides that extent as double-stranded DNA ending in a single-stranded 3′ overhang. READ MORE

  6. 4. Telomeres in ecology and evolution: Hypotheses and connections between telomere length, infections and life history trade-offs

    Author : David Gomez Blanco; MEMEG; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; telomeres; life history; telomere elongation; telomere shortening; early-life telomere length; critical threshold; malaria infection; great reed warbler; Acrocephalus arundinaceus;

    Abstract : Studying life history strategies is crucial for understanding the diversity among organisms. The trade-offs in traits related to survival, self-maintenance and reproduction play an important role in the variation of life histories and can be adjusted in response to environmental and physiological factors. READ MORE

  7. 5. Studies of molecular mechanisms of telomere maintenance in Naumovozyma castellii

    Author : Ahu Karademir Andersson; Molekylär cellbiologi; []
    Keywords : YEAST; Saccharomyces castellii; Naumovozyma castellii; Processvity; Telomerase; Telomere; ALT; Strain engineering;

    Abstract : Telomeres are special DNA-protein structures that protect ends of chromosomes from being recognized as double-strand breaks. Telomeres consist of tandemly repeated units of TG-rich DNA and associate with telomere-specific proteins. READ MORE