Search for dissertations about: "Telomeres"

Showing result 21 - 25 of 59 swedish dissertations containing the word Telomeres.

  2. 21. A short story of the long telomere : evidence in aging epidemiology

    Author : Yiqiang Zhan; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Telomeres are the sequences of nucleotides at the end of chromosomes. Each time a cell divides, telomeres become shorter. The length of telomeres can be replenished by an enzyme, telomerase. Telomere shortening is hypothesized as the biological origin of aging. READ MORE

  4. 22. Saccharomyces castellii: A new model organism for telomere research

    Author : Eimantas Astromskas; Biologiska institutionen; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Naumovia castellii; Saccharomyces castellii; yeast; genetic tools; gene targeting; telomere; CDC13.; telomeric overhang;

    Abstract : Telomeres are natural ends of eukaryotic chromosomes and perform a major role in cell biology. They protect chromosomes from degradation, fusions and the end replication problem. To study telomeres different model organisms are used including a number of yeast species. READ MORE

  5. 23. Repetitive DNA in search of a function - a study of telomeric and centromeric sequences in Chironomus

    Author : Casimiro Castillejo-Lopez; Udo Häckers grupp Utvecklingsbiologi i invertebrater; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Chironomus; CENP-B box; mobile elements; reverse transcriptase; gene conversion; satellite; repetitive DNA; Telomere; centromere; Genetics; cytogenetics; Genetik; cytogenetik;

    Abstract : Repetitive DNA is quantitatively the main component of telomeres and centromeres, structures responsible for maintenance of the eukaryotic chromosome. The telomere is the specialized nucleoprotein complex that terminates linear chromosomes. READ MORE

  6. 24. Guardians of the genome : Connecting chromatin structure and genome integrity in Saccharomyces cerevisiae

    Author : Stefanie Lena Bauer; Stefan U. Åström; Brian Luke; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; molekylär biovetenskap; Molecular Bioscience;

    Abstract : Branched DNA structures arise during recombination and during other DNA repair processes such as repair of stalled replication forks. One branched structure, the Holliday Junction (HJ), is a four-way junction that can connect sister chromatids or homologous chromosomes. We show a physical interaction between the HJ-cleaving enzyme Yen1 and Uls1. READ MORE

  7. 25. RAP1 at the Yeast Telomere

    Author : Johan Wahlin; Biologiska institutionen; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; cytogenetik; DNA-binding; Saccharomyces; yeast; telomeric repeat; telomere; RAP1; repressor activator protein 1; Genetics; cytogenetics; Genetik;

    Abstract : Telomeres are specialized complexes of DNA and proteins that cap and confer stability to the ends of eukaryotic chromosomes. The telomeric DNA of most eukaryotes is composed of tandemly arranged short repeats. Within the budding yeasts these repeats are diverged in length as well as in nucleotide composition. READ MORE