Search for dissertations about: "Teoretisk kemi och biologi"
Showing result 1 - 5 of 89 swedish dissertations containing the words Teoretisk kemi och biologi.
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1. Prediction, modeling, and refinement of protein structure
Abstract : Accurate predictions of protein structure are important for understanding many processes in cells. The interactions that govern protein folding and structure are complex, and still far from completely understood. However, progress is being made in many areas. Here, efforts to improve the overall quality of protein structure models are described. READ MORE
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2. Two aspects of simulating disorder
Abstract : Histatin 5, an intrinsically disordered protein (IDP) found in the saliva, has been investigated in two studies, and in two different perspectives. In the first study, the structural properties of a conjugated histatin 5 fragment is characterized in an effort to explain its enhanced fungicidal properties. READ MORE
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3. Calculations of Reaction Mechanisms and Entropic Effects in Enzyme Catalysis
Abstract : Ground state destabilization is a hypothesis to explain enzyme catalysis. The most popular interpretation of it is the entropic effect, which states that enzymes accelerate biochemical reactions by bringing the reactants to a favorable position and orientation and the entropy cost of this is compensated by enthalpy of binding. READ MORE
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4. α-Synuclein Fibril Formation and the Effects of Lipid Membranes
Abstract : Amyloid protein aggregation results in major disturbances of cellular processes in humans. The most common amyloid-related disorders are Alzheimer´s disease and Parkinson´s disease. Parkinson´s disease is charaterized by the formation of protein-rich aggregates that are deposited in neurons, termed Lewy bodies and Lewy neurites. READ MORE
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5. Design and engineering of human transferrin receptor 1 and its binding proteins
Abstract : The human transferrin receptor 1 (TfR) is central in maintaining adequate cellular iron levels with the iron carrier proteins transferrin (Tf) and ferritin (Ft). Known to bind TfR is also HFE, another iron regulatory protein, competing with Tf for receptor binding. READ MORE
