Search for dissertations about: "Testosterone 2010"

Showing result 1 - 5 of 12 swedish dissertations containing the words Testosterone 2010.

  2. 1. Actions of androgens and estrogens in experimental models of cardiovascular disease

    Author : Johan Bourghardt Fagman; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; AR; atherosclerosis; AAA; androgens; testosterone; 2-methoxyestradiol;

    Abstract : Men are at higher risk of developing both atherosclerotic cardiovascular disease and abdominal aortic aneurysm (AAA). Actions of sex steroids are hypothesized to underlie these gender differences. Testosterone, the major androgen, reduces atherosclerosis in male animal models but is suggested to promote AAA formation. READ MORE

  4. 2. Impact of Lifestyle, Hormones, and Genes on Breast Cancer

    Author : Maria Hietala; Bröstcancer-genetik; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Breast cancer; BRCA1; BRCA2; androgen receptor; CAG; GGC; polymorphism; htSNP; oral contraceptives; testosterone; breast-feeding; prolactin; premenopausal women; CYP2D; complementary and alternative medicin; antidepressants;

    Abstract : Approximately 7000 women are diagnosed and 1500 women die from breast cancer in Sweden every year. The aim of this thesis was to study the interplay of polymorphisms, hormone levels, lifestyle, and the use of concomitant medication in relation to risk and prognosis in two cohorts: one composed of young healthy women from high-risk breast cancer families and the other of breast cancer patients from the general population. READ MORE

  5. 3. Role of environmental toxins in chronic experimental arthrithis - in search for anti-inflammatory pathways of ethanol and nicotine

    Author : Sofia Silfverswärd Lindblad; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; rheumatoid arthritis; collagen-induced arthritis; ethanol; testosterone; nuclear factor kappa B; smoking; nicotine; NMDA; regulatory T cells;

    Abstract : Rheumatoid arthritis (RA) is a common systemic autoimmune disorder and a debilitating disease affecting 1% of the world population. The etiology of RA is an unresolved issue. Environmental factors such as alcohol intake and cigarette smoke have been described as contributing to the pathogenesis of RA. READ MORE

  6. 4. Glutamate modulates temporomandibular joint bone tissue resorption in patients with early rheumatoid arthritis

    Author : Anna‐Kari Hajati; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : The general aim was to investigate the occurrence and development of TMJ bone tissue resorption and to identify predictors for progression during the two first years with rheumatoid arthritis. The thesis comprises one cross‐sectional part and one longitudinal part. READ MORE

  7. 5. Sex-different control of hepatic metabolism in relation to insulin sensitivity

    Author : Carolina Gustavsson; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : The liver is a key metabolic organ. The liver has adapted to the different metabolic needs in men and women, and therefore responds in a sex-specific manner to various stimuli. READ MORE