Search for dissertations about: "Tfh cell"
Showing result 1 - 5 of 15 swedish dissertations containing the words Tfh cell.
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1. Pattern recognition and iNKT cell regulation of B cell activation
Abstract : The immune system protects individuals against infections but can cause disease if the response is unbalanced. Immune responses include both innate and adaptive response, and these systems are connected. As the first line of defense, innate immune responses are immediately induced upon infection. READ MORE
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2. B cell regulation in autoimmune disease
Abstract : Our immune system protects us from both foreign antigens and self-derived autoantigens by sophisticated regulation. During an immune response, the innate and adaptive parts of the immune system closely collaborate at every stage of the response. READ MORE
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3. Regulation of the germinal center response by T follicular helper cells and type I interferons
Abstract : The protective effect of most currently available vaccines is dependent on high-affinity antibodies and long lived B cell memory, which develop within organized structures of secondary lymphoid organs called germinal centers (GCs). GC formation is supported by T follicular helper (Tfh) cells, a subset of CD4+ T cells that develop in parallel to other effector T cells and specifically localizes to B cell follicles. READ MORE
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4. T-cell specificity and regulation in atherosclerosis
Abstract : Cardiovascular disease is the main cause of death in the world. The underlying cause in most cases is atherosclerosis, a chronic inflammatory disease. Subendothelial retention of lipoproteins triggers monocyte-derived macrophages and T-helper (Th) 1 cells to form lipid-laden atherosclerotic plaques in the artery wall. READ MORE
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5. Exploring lymphocyte subsets, autoantibodies and the effect of B cell targeted therapies in rheumatic diseases
Abstract : Nowadays, around 100 different diseases sort under the umbrella of rheumatic diseases(1). They involve different mechanisms and symptoms engaging joints, tendons, ligaments, bones, muscles but also vital organs like the kidneys nervous system and circulation. READ MORE