Search for dissertations about: "Tfh cell"

Showing result 1 - 5 of 7 swedish dissertations containing the words Tfh cell.

  1. 1. Regulation of the germinal center response by T follicular helper cells and type I interferons

    University dissertation from Faculty of Medicine, Lund University

    Author : Madelene Dahlgren; Lunds universitet.; Lund University.; [2016]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Germinal Center; T follicular helper cell; type I interferon; dendritic cell; adjuvant; differentiation; IgG;

    Abstract : The protective effect of most currently available vaccines is dependent on high-affinity antibodies and long lived B cell memory, which develop within organized structures of secondary lymphoid organs called germinal centers (GCs). GC formation is supported by T follicular helper (Tfh) cells, a subset of CD4+ T cells that develop in parallel to other effector T cells and specifically localizes to B cell follicles. READ MORE

  2. 2. T-cell specificity and regulation in atherosclerosis

    University dissertation from Stockholm : Karolinska Institutet, Dept of Medicine, Solna

    Author : Anton Gisterå; Karolinska Institutet.; Karolinska Institutet.; [2016]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Abstract : Cardiovascular disease is the main cause of death in the world. The underlying cause in most cases is atherosclerosis, a chronic inflammatory disease. Subendothelial retention of lipoproteins triggers monocyte-derived macrophages and T-helper (Th) 1 cells to form lipid-laden atherosclerotic plaques in the artery wall. READ MORE

  3. 3. Impaired response to HBV vaccination in HIV-1 infected children : immunopathological mechanisms

    University dissertation from Stockholm : Karolinska Institutet, Dept of Microbiology, Tumor and Cell Biology

    Author : Yonas Bekele Feyissa; Karolinska Institutet.; Karolinska Institutet.; [2018]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Abstract : HBV vaccination prevents HBV infection and related liver cancer. Immunological dysfunctions of Tfh and B cells in HIV-1 infected individuals may affect the response to HBV vaccine. READ MORE

  4. 4. Immune maturation and lymphocyte characteristics in relation to early gut bacteria exposure

    University dissertation from Stockholm : Department of Molecular Biosciences, The Wenner-Gren Institute, Stockholm University

    Author : Sophia Björkander; Stockholms universitet.; [2016]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Allergy; cell-free supernatant; chemokines; colonization; cytokines; FOXP3; immune-maturation; lactobacilli; lymphocytes; NK-cells; Staphylococcus aureus; unconventional T-cells; molekylär biovetenskap; Molecular Bioscience;

    Abstract : At birth, the immune system is immature and the gut microbiota influences immune maturation. Staphylococcus aureus (S. aureus) and lactobacilli are part of the neonatal gut microbiota and have seemingly opposite effects on the immune system. S. READ MORE

  5. 5. Mechanistic studies of the adjuvant effects of CTA1-DD and the native cholera toxin: Impact of cell targeting and tissue localization

    University dissertation from Göteborg : University of Gothenburg

    Author : Johan Mattsson; Göteborgs universitet.; Gothenburg University.; [2012]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Vaccines; adjuvants; cholera toxin; germinal center; CTA1-DD; follicular dendritic cells; denritic cells; Th1; Th2; Th17; complement;

    Abstract : Vaccines are the most effective means of preventing infectious diseases and improving global health. However, few vaccines have successfully been developed for protection at mucosal surfaces where most pathogens gain access. READ MORE