Search for dissertations about: "The complement system"

Showing result 1 - 5 of 410 swedish dissertations containing the words The complement system.

  1. 1. Crosstalk Between Activated Platelets and the Complement System

    University dissertation from Uppsala : Acta Universitatis Upsaliensis

    Author : Osama A. Hamad; Uppsala universitet.; [2010]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; platelets; activated platelets; TRAP; chondroitin sulfate; C1q; factor H; C4BP; C3; Compstatin; complement; platelet-leukocyte complexes; platelet microparticles; MEDICINE Microbiology; immunology; infectious diseases Immunology Clinical immunology; MEDICIN Mikrobiologi; immunologi; infektionssjukdomar Immunologi Klinisk immunologi; Klinisk immunologi; Clinical Immunology;

    Abstract : Several studies have shown that complement and thrombotic events co-exist. Platelets have been suspected to act as the bridge between the two cascade systems. READ MORE

  2. 2. The Role of IgM and Complement in Antibody Responses

    University dissertation from Uppsala : Acta Universitatis Upsaliensis

    Author : Christian Rutemark; Uppsala universitet.; [2011]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Complement; antibody response; mutated IgM; natural IgM; complement receptors; SIGN-R1; SAP; CRP; B cells; Medical Science; Medicinsk vetenskap;

    Abstract : An intact complement system including the complement receptors 1 and 2 (CR1/2) is crucial for the generation of a normal antibody response in animals and humans. Moreover, activation of the classical pathway is thought to be important since deficiency in complement components C1q, C2, C4 or C3 lead to impaired antibody responses. READ MORE

  3. 3. The complement system in stherosclerosis and arthritis

    University dissertation from Uppsala : Acta Universitatis Upsaliensis

    Author : Linda Persson; Göteborgs universitet.; Gothenburg University.; [2004]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; complement; C3; factor B; ASP; atherosclerosis; hyperlipidemia; arthritis;

    Abstract : The complement system plays an essential role in the humoral immune response. Activated complement has diverse functions, including the initiation of inflammation, recruitment of leukocytes, clearance of immune complexes, neutralization of pathogens, regulation of antibody responses and disruption of cell membranes. READ MORE

  4. 4. Recognition molecules of the complement system: C1q and mannan-binding lectin in autoimmunity and immune defence

    University dissertation from Department of Laboratory Medicine, Lund University

    Author : Ulla Mårtensson; Lunds universitet.; Lund University.; [2006]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; transplantation; serologi; Immunologi; Immunology; serology; autoantibodies; collectins; complement; autoimmunity; Infections; Infektioner;

    Abstract : Popular Abstract in Swedish C1q, en delkomponent av C1 molekylen, och mannan-bindande protein (MBL) är igenkänningsmolekyler i komplementsystemet. De har likartad struktur. C1q binder till IgG och IgM och aktiverar den klassiska vägen. MBL binder till kolhydratstrukturer och aktiverar lektinvägen. READ MORE

  5. 5. Complement aberrations and autoantibodies to complement proteins in relation to disease mechanisms

    University dissertation from Department of Laboratory Medicine, Lund University

    Author : Lillemor Melander Skattum; Lunds universitet.; Lund University.; [2008]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; C3 nephritic factors; GM allotypes; C1q autoantibodies; serum bactericidal activity; Neisseria meningitidis; idiopathic sudden hearing loss; complement; Acute poststreptococcal glomerulonephritis;

    Abstract : The complement system, a part of the innate immune system with several links to the adaptive immune system, plays an important role in the pathogenesis of many diseases. The purpose of this thesis was to document and clarify some of these mechanisms. The thesis is based on four papers (I-IV). READ MORE