Search for dissertations about: "Therapeutic immunization"

Showing result 6 - 10 of 52 swedish dissertations containing the words Therapeutic immunization.

  2. 6. Helicobacter pylori infection and immunity. Protection after vaccination and regulation of inflammation in a mouse model

    Author : Sukanya Raghavan; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Helicobacter pylori; formalin-inactivated H. pylori; post-immunization gastritis; cholera toxin; CD4 CD25 regulatory T cells; CpG ODN;

    Abstract : Helicobacter pylori infection is an important cause of chronic active gastritis and peptic ulcer disease and a risk factor for the development of gastric cancer. An attractive strategy in the control of H. pylori infection is the development of a safe and effective therapeutic vaccine. Using a mouse model of H. READ MORE

  4. 7. Studies of T- and B-cells for the generation of human antigen specific antibodies

    Author : Eva Andersson; Institutionen för immunteknologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; germinal center; CD4 CD57 T cells; mucin 1; in vitro immunization; human class switched antibodies; Biotechnology; Bioteknik;

    Abstract : Human antibodies generated in vitro may be highly valuable for diagnostic and therapeutic purposes. For a long time most human antibodies produced in vitro have been of the IgM isotype with rather low affinities. In this thesis a method for production of IgG switched antigen-specific human antibodies is presented. READ MORE

  5. 8. The impact of protein modification on immunogenicity and arthritogenicity

    Author : Ewa Westman; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Post translational modifications; chlorination; CII; CIA; RA; effect of therapeutic substance CDM for RA;

    Abstract : Rheumatoid arthritis (RA) is an inflammatory autoimmune disease affecting about 1% of the Western world population. There are several theories regarding the etiopathogenesis. READ MORE

  6. 9. Combined chemotherapy and immunotherapy against experimental malignant brain tumors

    Author : Sara Fritzell; Neurokirurgi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Cisplatin; Glioma; GM-CSF; IFN-gamma; IL-7; Immunotherapy; Intratumoral chemotherapy; Temozolomide;

    Abstract : Glioblastoma multiforme (GBM) is the most common and aggressive primary malignant brain tumor in adults. Despite standard treatment including surgery, radiotherapy and temozolomide (TMZ)-based chemotherapy, the prognosis for GBM patients is dismal, and there is a need for novel treatments. READ MORE

  7. 10. Mechanisms and modulation of experimental allergic encephalomyelitis as basis for treatment of multiple sclerosis

    Author : Ling-Yun Xu; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Background: Multiple sclerosis (MS) is a chronic inflammatory demyelinating disease of the central nervous system (CNS). Its etiology is unknown and there exists no cure. READ MORE