Search for dissertations about: "Thermodynamic Stability"

Showing result 1 - 5 of 132 swedish dissertations containing the words Thermodynamic Stability.

2. 1. SOD1 Aggregation : Relevance of thermodynamic stability

   Author : Lisa Lang; Mikael Oliveberg; Michele Vendruscolo; Stockholms universitet; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; Aggregation; misfolding; Superoxide dismutase SOD1 ; Amyotrophic lateral sclerosis ALS ; unfolding; thermodynamic stability; Biochemistry; biokemi;

   Abstract : Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease affecting the upper and lower motor neurons causing muscle atrophy and paralysis followed by death. Aggregates containing superoxide dismutase (SOD1) are found as pathological hallmark in diseased ALS patients. READ MORE

4. 2. Disordered Icosahedral Boron-Rich Solids : A Theoretical Study of Thermodynamic Stability and Properties

   Author : Annop Ektarawong; Björn Alling; Michael Widom; Linköpings universitet; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; Icosahedral boron-rich solids; Boron carbide; Configurational disorder; First-principles calculations; Thermodynamic stability; Superatom-special quasirandom structure;

   Abstract : This thesis is a theoretical study of configurational disorder in icosahedral boron-rich solids, in particular boron carbide, including also the development of a methodological framework for treating configurational disorder in such materials, namely superatom-special quasirandom structure (SA-SQS). In terms of its practical implementations, the SA-SQS method is demonstrated to be capable of efficiently modeling configurational disorder in icosahedral boron-rich solids, whiles the thermodynamic stability as well as the properties of the configurationally disordered icosahedral boron-rich solids, modeled from the SA-SQS method, can be directly investigated, using the density functional theory (DFT). READ MORE

5. 3. Phase equilibria and thermodynamic properties of high-alloy tool steels : theoretical and experimental approach

   Author : Johan Bratberg; John Ågren; Bengt Hallstedt; KTH; []
   Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; thermodynamic modelling; thermodynamic calculations; tool steels; high-speed steels; CALPHAD; Other materials science; Övrig teknisk materialvetenskap;

   Abstract : The recent development of tool steels and high-speed steels has led to a significant increase in alloy additions, such as Co, Cr, Mo, N, V, and W. Knowledge about the phase relations in these multicomponent alloys, that is, the relative stability between different carbides or the solubility of different elements in the carbides and in the matrix phase, is essential for understanding the behaviour of these alloys in heat treatments. READ MORE

6. 4. Unravelling protein stability and aggregation

   Author : Tanja Weiffert; NanoLund: Centre for Nanoscience; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; protein stability; protein aggregation; amyloid beta peptide; protein stabilization; split GFP; monellin; secretagogin; ; aggregation kinetics; toxicity; aggregation mechanism; coaggregation;

   Abstract : Proteins are complex macromolecules that are fundamental to all living species. The stability of proteins are governed by non-covalent forces within the protein and between the protein and its surrounding environment. READ MORE

7. 5. Protein stability and mobility in live cells : Revelation of the intracellular diffusive interaction organization mechanisms

   Author : Xin Mu; Mikael Oliveberg; Johan Elf; Stockholms universitet; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; diffusive interactions; macromolecular crowding; protein thermodynamic stability; protein mobility; in-cell NMR; Hofmeister series; Biochemistry; biokemi;

   Abstract : Biochemical processes inside living cells take place in a confined and highly crowded environment. As such, macromolecular crowding, one of the most important physicochemical properties of cytoplasm, is an essential element of cell physiology. READ MORE