Search for dissertations about: "Thesis on pathology"

Showing result 1 - 5 of 736 swedish dissertations containing the words Thesis on pathology.

  2. 1. Ageing-associated changes of lysosomal compartment : implications on cellular functions

    Author : Yuri Stroikin; Ulf Brunk; Alexei Terman; Karin Öllinger; Suresh Rattan; Linköpings universitet; []
    Keywords : LANTBRUKSVETENSKAPER; AGRICULTURAL SCIENCES; Ageing; Apoptosis; Biological gabarge; Hormesis; Lipofuscin; Lysosome; Pathology; Patologi;

    Abstract : The lysosomal compartment is a major site for intracellular degradation. Lysosomal degradation of the cell’s own constituents, so-called autophagy, not only provides a cell with nutrients, but also removes damaged and potentially dangerous endogenous structures, thus securing intracellular homeostasis. READ MORE

  4. 2. Medin amyloid - a matter close to the heart : Studies on medin amyloid formation and involvement in aortic pathology

    Author : Annika Larsson; Per Westermark; Sari Kiuru-Enari; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; AA amyloidosis; aging; amyloid; aneurysm; arterial media; dissection; elastin; medin amyloid; lactadherin; thoracic aorta; Pathology; Patologi;

    Abstract : Amyloidoses are a group of protein misfolding diseases characterized by deposits of insoluble fibrillar protein aggregates. Medin amyloid, which is the focus of this thesis, appears in the media of the thoracic aorta in nearly all individuals over 50 years. READ MORE

  5. 3. The CpG island methylator phenotype in colorectal cancer : studies on risk and prognosis

    Author : Anna Dahlin; Richard Palmqvist; Bethany van Guelpen; Maria Henriksson; Åke Öberg; Xiao-Feng Sun; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Colorectal cancer; DNA methylation; folate; microsatellite instability MSI ; prognosis; risk factors; t-lymphocytes; the CpG island methylator phenotype CIMP ; Vitamin B12; Pathology; Patologi; Tumour biology; Tumörbiologi; patologi; Pathology;

    Abstract : Background Colorectal cancer (CRC) is the second most common malignancy in developed countries. The mortality is high, with nearly half of patients dying from the disease. The primary treatment of CRC is surgery, and decisions about additional treatment with chemotherapy are based mainly on tumor stage. READ MORE

  6. 4. Prognostic markers in prostate cancer : studies of a watchful waiting cohort with long follow up

    Author : Andreas Josefsson; Anders Bergh; Pernilla Wikström; Pär Stattin; Anders Bjartell; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Prostate cancer; Immunohistochemistry; Prognostic markers; biomarkers; Survival analysis; human; pathology; watchful waiting; tissue micro array; Endoglin; von willebrandt factor; ki67; ki-67; hyaluronan; patologi; Pathology;

    Abstract : Background: Prostate Cancer (PC) is a common and highly variable disease. Using current diagnostic methods, the prostate specific antigen (PSA) blood test and histological grading of prostate tissue needle biopsies, it is often difficult to evaluate whether the patient has a PC that requires active treatment or not. READ MORE

  7. 5. Studies on Human Endogenous Retroviruses (HERVs) with Special Focus on ERV3

    Author : Ann-Catrin Andersson; Bengt Widegren; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Genetics; human endogenous retroviruses; HERV; ERV3; expression; in situ hybridisation; real-time PCR; U-937; retinoic acid.; Genetik; Clinical genetics; Klinisk genetik; Pathology; patologi;

    Abstract : Human endogenous retroviruses (HERVs) represent approximately 7% of the human genome. This investigation was focused on one particular HERV, ERV3, with the main purpose of characterising its gene expression patterns and genomic distribution of ERV3-like sequences. READ MORE