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Found 4 swedish dissertations matching the above criteria.
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1. Multidrug-Resistant Escherichia coli and Klebsiella pneumoniae : Treatment, Selection and International Spread
Abstract : The prevalence of Escherichia coli and Klebsiella pneumoniae producing extended-spectrum beta-lactamases (ESBLs) and carbapenemases is increasing worldwide. Therapeutic options for infections with these bacteria are limited not only by the production of ESBLs and carbapenemases, which confer resistance to cephalosporins and carbapenems, but also by frequent co-resistance to other antibiotics. READ MORE
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2. β-lactam combinations against multidrug-resistant Enterobacterales : Exploring combination effects and resistance development
Abstract : The β-lactam antibiotics are a cornerstone in treating bacterial infections, but the increasing prevalence of antibiotic resistance worldwide threatens their effectiveness. The main driver of β-lactam resistance is the production of β-lactamases, which are bacterial enzymes that inactivate the antibiotic. READ MORE
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3. Development of a robust and rapid microfluidics-based antibiotic susceptibility test : From prototype to clinical implementation
Abstract : Even though bacteria normally are rapidly cleared from the blood by the immune system, a blood stream infection may arise, in turn possibly leading to sepsis and septic shock. Sepsis is a life-threatening condition, where the inflammatory response to infection targets tissues and organs. READ MORE
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4. Exploring the interactions of antibiotic combinations against multidrug-resistant Gram-negative bacteria
Abstract : Antimicrobial resistance is emerging and available treatment options are lacking. Antibiotics is a cornerstone in modern medicine where medical procedures such as surgery, care of premature babies or treatment of cancer is dependent on efficient drugs. READ MORE