Search for dissertations about: "Tissue culture"

Showing result 6 - 10 of 401 swedish dissertations containing the words Tissue culture.

  2. 6. Recombinant spider silk for biomedical applications - from functionalizing surfaces of synthetic materials to in vitro modelling of tissues

    Author : Christos Panagiotis Tasiopoulos; My Hedhammar; Antonella Motta; KTH; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; recombinant spider silk; surface functionalization; in vitro tissue models; membrane-based models; barrier tissues; cell co-culture; tissue engineering; Bioteknologi; Biotechnology;

    Abstract : Spider silk is a natural protein-based material known for its medicinal use and remarkable mechanical properties. Structures made thereof are both strong and elastic and have been shown to be favorable matrices for tissue engineering. READ MORE

  4. 7. Spider Silk Nanostructuring and its Applications for Tissue Engineering

    Author : Linnea Gustafsson; Wouter van der Wijngaart; David Kaplan; KTH; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; recombinant spider silk; nanostructures; microstrucutres; nanowires; nanochains; nanodisks; nanomembranes; tissue engineering; in-vitro models; medical technology; health technology; nanomedicine; rekombinant spindelsilke; nanostrukturer; mikrostrukturer; nanotrådar; nanokedjor; nanodiskar; nanomembran; vävnadsteknik; in vitro-modeller; medicinsk teknik; hälsoteknik; nanomedicin; Electrical Engineering; Elektro- och systemteknik;

    Abstract : This thesis introduces new ways to produce micro-and nanostructures of recombinant spider silk and explores ways to characterize their topography, mechanical properties, cell compatibility, and permeability. The suitability of the formed structures for applications within tissue engineering, primarily in vitro tissue modeling, is also investigated. READ MORE

  5. 8. Hyaluronan Based Biomaterials with Imaging Capacity for Tissue Engineering

    Author : Yu Zhang; Dmitri Ossipov; Carsten Werner; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; hyaluronan; hydrogel; scaffold; tissue engineering; imaging; interpenetrating network; MRI; fluorescence imaging; scaffold degradation;

    Abstract : This thesis presents the preparation of hyaluronan-based biomaterials with imaging capability and their application as scaffolds in tissue engineering. First, we have synthesized HA derivatives functionalized with different chemoselective groups. READ MORE

  6. 9. Studies on various culture systems for chondrocytes and osteoblasts

    Author : Juha Prittinen; Mikko Lammi; Minna Kellomäki; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Cell biology; chondrocyte; osteoarthritis; surface materials; topography; tissue engineering; mechanical stimulation; Medical Cell Biology; medicinsk cellbiologi;

    Abstract : Osteoarthritis and osteochondral defects are ailments that are increasing in frequency as the lifespan of the population increases and sedentary lifestyle becomes more common. Osteoarthritis is an inflammatory disease that causes the progressive degeneration of articular surfaces and the underlying bone. READ MORE

  7. 10. Proteomics informed investigation of human hepatocytes and liver tissue

    Author : Niklas Handin; Per Artursson; Peter Nygren; Tobias Sjöblom; Mårten Fryknäs; Pieter Annaert; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; human; liver; hepatocytes; proteomics; cellular stress; apoptosis; hepatotoxicity; 3D culture; spheroid; drug metabolism; drug toxicity; drug transport; Farmaceutisk vetenskap; Pharmaceutical Science;

    Abstract : A successful drug needs to display beneficial absorption, distribution, metabolism, excretion and toxicity (ADME-Tox) profile. It is therefore important to investigate these properties during the drug discovery process. READ MORE