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Showing result 1 - 5 of 22 swedish dissertations matching the above criteria.

  2. 1. Fatigue assessments of components in construction equipment

    Author : Anders Tjernberg; KTH; []
    Keywords : engineering mechanical;

    Abstract : The thesis refers to "Fatigue Assessment of Components inConstruction Equipment". The subject was chosen because ofincreasing interest in higher payloads, lower weight, highervelocities and shorter load cycles in construction equipmentvehicles. READ MORE

  4. 2. Protein mass spectrometry in the drug discovery process

    Author : Agneta Tjernberg; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Mass spectrometry; ESI-MS; MALDI-TOF MS; drug discovery; protein characterization; dissociation constants;

    Abstract : Most targets for drug discovery are proteins. Drug discovery includes target identification and validation, structural biology, lead generation, lead optimisation, pre-clinical development and clinical trials. The overall aim of this thesis is to apply protein mass spectrometry (MS) in the early drug discovery process. READ MORE

  5. 3. Molecular basis and pharmacological implications of Alzheimer amyloid ß-peptide fibril formation

    Author : Lars Tjernberg; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Alzheimer s disease; amyloid; fibrils; inhibitor; protease resistance; electron microscopy; fluorescence correlation spectroscopy.;

    Abstract : Alzheimer's disease is a progressive neurodegenerative disease, mostly affecting elderly. The invariable deposition of protease-resistant fibrils of Alzheimer amyloid ß-peptide (Aß) in the parenchyma and blood vessels of the brain is a central event. READ MORE

  6. 4. Photoelectron spectroscopy on strongly correlated systems

    Author : Oscar Tjernberg; KTH; []
    Keywords : ;

    Abstract : This work presents photoelectron spectroscopy data on somestrongly correlated systems. The electronic structure of the3dtransition metal oxides NiO and CoO have been studiedwith angle resolved and resonant photoemission. In the lattercase, both NiO and CoO show strong resonance effects at themetal absorption edges. READ MORE

  7. 5. Laboratory Diagnosis of Lyme Borreliosis : Anti-Borrelia Antibodies and the Chemokine CXCL13

    Author : Ivar Tjernberg; Pia Forsberg; Jan Ernerudh; Ingvar Eliasson; Ingvar Rydén; Fredrik Elgh; Linköpings universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Infectious diseases; Infektionssjukdomar;

    Abstract : Lyme borreliosis (LB), the most common tick-borne disease in Europe and North America, is caused by spirochetes of the Borrelia burgdorferi sensu lato complex. The spirochetes can invade several different organs, thereby causing many different symptoms and signs. READ MORE