Search for dissertations about: "Tor Olofsson"

Found 5 swedish dissertations containing the words Tor Olofsson.

2. 1. Anti-TNF therapy in rheumatoid arthritis. Effects on and predictors of work disability

   Author : Tor O Olofsson; Reumatologi och molekylär skelettbiologi; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

   Abstract : Objectives: To study: (I) work-loss seen as sick leave and disability pension before and after the start of first anti-TNF therapy in Swedish regional and national RA cohorts; (II) baseline predictors of a good future work prognosis at diagnosis and after anti-TNF start with a special focus on the impact of the disease activity level and the disease duration at treatment start. Methods: RA patients were identified in the regional biologics register in Southern Sweden, SSATG, the national register over RA patients, SRQ, and the national biologics register, ARTIS, and linkage was performed to the Social Insurance Agency Register for day-level data on sick leave and disability pension. READ MORE

4. 2. Characterization of proteins involved in differentiation and apoptosis of human leukemia and epithelial cancer cells

   Author : Veronika Viktorija Borutinskaite; Karl Eric Magnusson; Ruta Navakauskiene; Tor Olofsson; Linköpings universitet; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; leukemia; histone deacetylase inhibitors; retinoic acid; differentiation; apoptosis; Cell and molecular biology; Cell- och molekylärbiologi;

   Abstract : Today, cancer is understood as an epigenetic as well as a genetic disease. The main epigenetic hallmarks of the cancer cell are DNA methylation and histone modifications. The latter changes may be an optimal target for novel anticancer agents. READ MORE

5. 3. Mast cells in Hodgkin lymphoma : or 'What's a nice cell like you doing in a tumour like this?'

   Author : Marie Fischer; Gunnar Nilsson; Gunilla Enblad; Tor Olofsson; Uppsala universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pathology; Hodgkin lymphoma; mast cells; CD30; CD30L; IL-9; CCL5; atopic dermatitis; psoriasis; IL-8; Patologi; Pathology; Patologi;

   Abstract : Mast cell (MC) accumulation around tumours is an old observation gaining new relevance due to the multifaceted nature of MCs and their many roles in immunity, beyond allergy. Knowledge about tumour specific recruitment of, and interactions with, MCs is needed to unravel the function of their presence. READ MORE

6. 4. New aspects on retinoic acid induced HL-60 granulocytic differentiation

   Author : Agnè Kulytè; Tor Olofsson; Linköpings universitet; []
   Keywords : MEDICINE; MEDICIN;

   Abstract : The underlying mechanisms of myeloid cell differentiation are still not entirely elucidated. It is therefore an urgent task to extent the basis for a comprehensive model of granulocytes differentiation. A primary goal for studies has been the identification of differentiation markers. READ MORE

7. 5. Learning to be at a distance : structural and educational change in the digitalization of medical education

   Author : Fanny Pettersson; Anders D. Olofsson; Tor Söderström; Christina Ljungberg; Andreas Lund; Umeå universitet; []
   Keywords : SAMHÄLLSVETENSKAP; SOCIAL SCIENCES; Distance education; medical education; medical program; regionalized medical program; rural clinical school; digitalization; digital technologies; technology-enhanced learning; TEL; cultural-historical activity theory; CHAT; transition; transformation; conflicts; contradictions; dominant- non-dominant activities; levels of learning; pedagogik; Education;

   Abstract : As an expression of current challenges faced by contemporary societies, past decades have witnessed heavy demands for higher education to change and transform. One key question here has been the increased digitalization of higher education. READ MORE