Search for dissertations about: "Torgeir Hvidsten"

Found 4 swedish dissertations containing the words Torgeir Hvidsten.

2. 1. Predicting Function of Genes and Proteins from Sequence, Structure and Expression Data

   Author : Torgeir R. Hvidsten; Anna Tramontano; Uppsala universitet; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; Bioinformatics; Bioinformatik; Bioinformatics; Bioinformatik;

   Abstract : Functional genomics refers to the task of determining gene and protein function for whole genomes, and requires computational analysis of large amounts of biological data including DNA and protein sequences, protein structures and gene expressions. Machine learning methods provide a powerful tool to this end by first inducing general models from such data and already characterized genes or proteins and then by providing hypotheses on the functions of the remaining, uncharacterized cases. READ MORE

4. 2. Evolution of the G protein-coupled receptor signaling system : Genomic and phylogenetic analyses

   Author : Arunkumar Krishnan; Helgi Schiöth; Torgeir Hvidsten; Uppsala universitet; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; GPCRs; G proteins; Sensory system; Signal transduction; Olfaction; Chemosensation; Hemichordates; Sponges; Porifera; Bilaterians; Holozoans; Fungi; Opisthokonts; Bioinformatics; Bioinformatik;

   Abstract : Signal transduction pathways mediated by G protein-coupled receptors (GPCRs) and their intracellular coupling partners, the heterotrimeric G proteins, are crucial for several physiological functions in eukaryotes, including humans. This thesis describes a broad genomic survey and extensive comparative phylogenetic analysis of GPCR and G protein families from a wide selection of eukaryotes. READ MORE

5. 3. Chemogenomics: Models of Protein-Ligand Interaction Space

   Author : Helena Strömbergsson; Gerard J Kleywegt; Jarl E S Wikberg; Torgeir R Hvidsten; John Overington; Uppsala universitet; []
   Keywords : ;

   Abstract : The large majority of the currently used drugs are small molecules that interact with proteins. Understanding protein-ligand recognition is thus central to drug discovery and design. Improved experimental techniques have resulted in an immense growth of drug target information. READ MORE

6. 4. Novel resources enabling comparative regulomics in forest tree species

   Author : David Sundell; Torgeir Hvidsten; Klaas Vandepoele; Umeå universitet; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; Comparative genomics; Web resource; Wood development; RNA-Seq; Forestry; Lignocellulose; Regulomics; High-spatial resolution; Populus tremula; Picea abies; Orthology.; biology; biologi; molekylär bioteknik inst f nat vet biokemi ; molecular biotechnology dept of biochem ;

   Abstract : Lignocellulosic plants are the most abundant source of terrestrial biomass and are one of the potential sources of renewable energy that can replace the use of fossil fuels. For a country such as Sweden, where the forest industry accounts for 10% of the total export, there would be large economical benefits associated with increased biomass yield. READ MORE