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Showing result 1 - 5 of 18 swedish dissertations matching the above criteria.

  2. 1. Aspects on wall properties of the brachial artery in man : with special reference to SLE and insulin-dependent diabetes mellitus

    Author : Niclas Bjarnegård; Toste Länne; Reinhard Volkmann; Linköpings universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Arterial wall; atherosclerotic; brachial artery BA ; type 1 diabetes; ulse wave velocity PWV ; pulse wave analysis PWA ; intima-media thickness IMT ; nitrate mediated dilatation NMD ; Diabetology; Diabetologi;

    Abstract : The mechanical properties of the arterial wall are of great importance for blood pressure regulation and cardiac load. With increasing age, large arteries are affected by increased wall stiffness. READ MORE

  4. 2. Vessel wall integrity : influence of genetics and flow

    Author : Hanna Björck; Toste Länne; Per Eriksson; Sverker Jern; Linköpings universitet; []
    Keywords : ;

    Abstract : Cardiovascular disease (CVD) is the major cause of death worldwide. Underlying causes, such as atherosclerosis and hypertension, are associated with remodeling of the vessel wall ultimately leading to loss of structural integrity. There are a number of factors that can influence vascular remodeling and hence structural integrity. READ MORE

  5. 3. VEGF-mediated vascular functions in health and disease

    Author : Ziquan Cao; Eric Wahlberg; Yihai Cao; Toste Länne; Kayoko Hosaka; Jack L. Arbiser; Linköpings universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Abstract : Angiogenesis is essential for physiological processes including embryonic development, tissue regeneration, and reproduction. Under various pathological conditions the same angiogenic process contribute to the onset, development, and progression of many human diseases including cancer, diabetic complications, ocular disease, chronic inflammation and cardiovascular disease. READ MORE

  6. 4. Markers of subclinical atherosclerosis and arterial stiffness in type 2 diabetes

    Author : Elsa Dahlén; Carl Johan Östgren; Toste Länne; Fredrik Nyström; Lars Lind; Linköpings universitet; []
    Keywords : MEDICINE; MEDICIN;

    Abstract : Background: Type 2 diabetes is a common disease with increased mortality and morbidity due to cardiovascular disease (CVD). This thesis is based on three studies that evaluated traditionally used and emerging risk markers to identify individuals with high-risk of developing CVD in middle-aged men and women with type 2 diabetes. READ MORE

  7. 5. Influence of genetics and mechanical properties on large arteries in man

    Author : Rachel De Basso; Toste Länne; Martin Björck; Linköpings universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Abstract : Arterial pathology is the major contributor to cardiovascular diseases and mortality. The mechanical properties of arteries are independent factors for cardiovascular disease and mortality, where genetics influence the structure of the arterial wall, which may result in change in arterial stiffness. READ MORE