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Found 3 swedish dissertations matching the above criteria.

  2. 1. New Approaches for Daphnia magna Toxicity Assessment

    Author : Berkay Paylar; Per-Erik Olsson; Jana Jass; Solomon Asnake; Ajay Pradhan; Joachim Sturve; Örebro universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Risk assessment; toxicogenomics; zinc; copper; machine learning;

    Abstract : Risk assessment plays a crucial role in evaluating and managing the potential hazards and health effects associated with exposure to substances. In recent decades, the field of risk assessment has undergone significant expansion, embracing innovative approaches and methodologies. READ MORE

  4. 2. Pluripotent Stem Cells of Embryonic Origin : Applications in Developmental Toxicology

    Author : Måns Jergil; Lennart Dencker; Aldert Piersma; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Embryonic stem cell; Microarray; Toxicogenomics; Valproic acid; Developmental toxicology; Teratogenicity; Neural tube defects; Histone deacetylase inhibitor; In vitro toxicology; Toxicology; Toxikologi; Toxicology; Toxikologi;

    Abstract : General toxicity evaluation and risk assessment for human exposure is essential when developing new pharmaceuticals and chemicals. Developmental toxicology is an important part of this risk assessment which consumes large resources and many laboratory animals. READ MORE

  5. 3. Transcriptomics and Proteomics Applied to Developmental Toxicology

    Author : Kim Kultima; Lennart Dencker; Timothy Gant; Uppsala universitet; []
    Keywords : Toxicology; 2D-DIGE; Valproic acid; PBDE-99; Flame retardant; Neural tube defects; Microarray; In vivo; In vitro; Biomarker; Brain growth spurt; Normalization; Mouse embryo; Toxicogenomics; Toxikologi;

    Abstract : Developmental toxicology is an important part of preclinical drug toxicology as well as environmental toxicology. Assessing reproductive and developmental toxicity is especially expensive and time demanding, since at least two generations of animals are needed in the tests. READ MORE