Search for dissertations about: "Transcription factors"

Showing result 11 - 15 of 946 swedish dissertations containing the words Transcription factors.

  2. 11. Regulators of chromatin and transcription in Drosophila

    Author : Filip Crona; Mattias Mannervik; Fernando Azorin; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Transcription; chromatin; co-regulators; CBP; lysine demethylase; KDM4A; Brakeless; Drosophila; utvecklingsbiologi; Developmental Biology;

    Abstract : Development of multicellular organisms is achieved by organized temporal and spatial patterns of gene expression leading to cell differentiation. Chromatin regulators control how the DNA is utilized by altering access of proteins to DNA and thereby function as co-factors in transcription. READ MORE

  4. 12. Regulation of Human Mitochondrial DNA Replication and Transcription

    Author : Majda Mehmedovic; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Mitochondria; mtDNA; replication; transcription; TFAM;

    Abstract : Mitochondria are organelles in eukaryotic cells, which through oxidative phosphorylation (OXPHOS) produce most of the ATP used to drive cellular processes. The organelle contains its own genetic material, mitochondrial DNA (mtDNA), which encodes 13 key components of the OXPHOS machinery. READ MORE

  5. 13. Role of POU/Oct transcription factors in Drosophila immunity

    Author : Widad Dantoft; Ylva Engström; Anne Uv; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Antimicrobial peptides; Drosophila; host-pathogen interaction; immune gene expression; immune signaling; NF-kB; microbiota; POU Oct transcription factors; protein degradation; stress response; transcriptional regulation; Molecular Biology; molekylärbiologi;

    Abstract : In response to infection, Drosophila melanogaster relies on the ability to mount a robust and potent innate immune response, characterized by induction of cellular and humoral processes. While rapid immune induction is of utmost importance, it is equally important to restrict and repress immune gene expression, where and when it is not needed. READ MORE

  6. 14. Structure-function relationships of the human Runx1 transcription factor

    Author : Magnus Wolf-Watz; KTH; []
    Keywords : Runx1; Runt domain; CBFâ; transcription; leukemia; protein structure; protein dynamics;

    Abstract : Runx transcription factors contain a DNA-binding andtransactivating α-subunit and a β-subunit (CBFβ)that serves to increase the DNA binding affinity of theα-subunit. The DNA binding domain of Runx proteins isnamed the Runt homology domain (RD) after its strong sequencehomology to theDrosophilaprotein Runt. READ MORE

  7. 15. Viral Strategies to Regulate Transcription and Pre-mRNA Splicing

    Author : Shaoan Fan; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Biochemistry; Adenovirus E1B-55kDa; E4-ORF4; E4-ORF6 proteins; L1 mRNA; Polyoma virus small T antigen; regulation; transcription; splicing; PP2A; Biokemi; Biochemistry; Biokemi; Medical Virology; medicinsk virologi;

    Abstract : A typical DNA virus encodes for a few key regulatory proteins that modify the host cell biosynthetic machinery to achieve a selective viral gene statement. One such example is illustrated by the adenovirus E4-ORF4 protein, which form an enzymatically active complex with the serine and threonine-specific protein phosphatase 2A (PP2A). READ MORE