Search for dissertations about: "Transcription termination"
Showing result 16 - 20 of 25 swedish dissertations containing the words Transcription termination.
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16. Regulation of mitochondrial gene expression in metazoa
Abstract : Mitochondria are essential organelles of eukaryotic cells and their main function is to provide the cell with the ubiquitously used energy currency ATP. Impaired energy conversion caused by mitochondrial dysfunction is a direct cause of several human diseases. READ MORE
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17. Gene Regulation and Epigenetic Mechanisms in the Parasite Trypanosoma cruzi
Abstract : Trypanosomes are unicellular protozoan parasites responsible for several human diseases that affect millions of people and cause thousands of casualties every year. They also represent a primitive eukaryotic model system harboring unique processes and basic regulatory mechanisms such as RNA-editing, polycistronic transcription and trans-splicing, first described in these organisms. READ MORE
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18. Molecular mechanisms of nociception in the rat brain : anatomical connections and trans-synaptic regulation of gene expression of neurons in the pontine parabrachial nucleus
Abstract : The pontine parabrachial nucleus (PB) is a major recipient of fibers fromnociceptive (pain-responsive) spinal and trigeminal dorsal horn neurons. With the use of combinations of molecular and morphological techniques, the anatomical connections of PB neurons and their expression of neuropeptide genes and transcription factors were studied, both in naive rats and in rats that had been subjected to nociceptive stimulation. READ MORE
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19. SUMO and ubiquitin : the yin and yang of IGF-1R function
Abstract : Tumorigenesis is a multistep process involving genetic and epigenetic alterations that drive the progressive transformation of normal human cells into highly malignant derivatives. The insulin-like growth factor 1 receptor (IGF-1R) plays pivotal roles in cancer. READ MORE
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20. Regulation of G2 phase and long-term consequences of DNA damage
Abstract : Cell proliferation requires the accurate replication of DNA and equal segregation of replicated genes, important for maintaining the integrity of newly formed cells. At the centre of this process is a series of coordinated events termed ‘the cell cycle’, which ensures cell proliferation proceeds with high fidelity. READ MORE