Search for dissertations about: "Transcriptional factors"

Showing result 1 - 5 of 493 swedish dissertations containing the words Transcriptional factors.

  2. 1. Unravelling Mechanistic Insights of Eukaryotic Transcriptional Control

    Author : Johanna Hörberg; Göteborgs universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Transcriptional control; Gene expression regulation; DNA supercoiling; DNA methylation; DNA-protein recognition; Basic-Leucine-Zipper transcription factors; Basic-Helix-Loop-Helix transcription factors; Sequence specific DNA plasticity; Transcription factor cooperativity; Cancer; Molecular modelling; Molecular dynamics;

    Abstract : DNA transcription involves the association of multiple proteins with DNA to convert the genetic information into messenger-RNA transcripts, which later will be translated into proteins. Con-trolled regulation of transcription is imperative for preserving the healthy and homeostatic state of cells. READ MORE

  4. 2. The Drosophila POU/Oct factors: multifaceted proteins

    Author : Priya Gohel; Ylva Engström; Mariana Wolfner; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; POU Oct factors; transcriptional regulation; innate immunity; developmental processes; mitotic spindles; chromosome segregation; molekylär biovetenskap; Molecular Bioscience;

    Abstract : Dysregulation of physiological and cellular processes underlies various pathological conditions, including cancer and inflammatory disorders. Unraveling the molecular mechanisms driving these processes is crucial. READ MORE

  5. 3. Role of POU/Oct transcription factors in Drosophila immunity

    Author : Widad Dantoft; Ylva Engström; Anne Uv; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Antimicrobial peptides; Drosophila; host-pathogen interaction; immune gene expression; immune signaling; NF-kB; microbiota; POU Oct transcription factors; protein degradation; stress response; transcriptional regulation; Molecular Biology; molekylärbiologi;

    Abstract : In response to infection, Drosophila melanogaster relies on the ability to mount a robust and potent innate immune response, characterized by induction of cellular and humoral processes. While rapid immune induction is of utmost importance, it is equally important to restrict and repress immune gene expression, where and when it is not needed. READ MORE

  6. 4. Nuclear receptor corepressor N-CoR : role in transcriptional repression

    Author : Kristina Loinder; Mats Söderström; Eckardt Treuter; Linköpings universitet; []
    Keywords : MEDICINE; MEDICIN;

    Abstract : The human body consists of a multitude of cells of varying appearance and function. With a few exceptions they are genetically identical, and the key to their divergence lies in their different specific patterns of gene expression. READ MORE

  7. 5. An analytical framework for studying transcriptional regulation

    Author : Christoph Sebastian Börlin; Chalmers tekniska högskola; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; transcription factor; ChIP-exo; S. cerevisiae; transcriptional regulation;

    Abstract : The state and behavior of any living cell is controlled by a complex interplay of different regulatory processes, with the regulation of transcription playing a major role. When a cell adapts to a new environment it often does that by modulating gene transcript levels, mainly through changes in transcription factor binding events. READ MORE