Search for dissertations about: "Transcriptional"

Showing result 1 - 5 of 1226 swedish dissertations containing the word Transcriptional.

  2. 1. The Multifunctional HnRNP A1 Protein in the Regulation of the Cyp2a5 Gene : Connecting Transcriptional and Posttranscriptional Processes

    Author : Tina Glisovic; Matti Lang; Francoise Raffalli-Mathieu; Lorenz Poellinger; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pharmaceutical biochemistry; Cyp2a5; DNA-protein interaction; gene regulation; hnRNP A1; nucleocytoplasmic shuttling; RNA-protein interaction; RNA stabilization; posttranscriptional; transcriptional; Farmaceutisk biokemi; Pharmaceutical biochemistry; Farmaceutisk biokemi;

    Abstract : The mouse xenobiotic-inducible Cyp2a5 gene is both transcriptionally and posttranscriptionally regulated. One of the most potent Cyp2a5 inducers, the hepatotoxin pyrazole, increases the CYP2A5 mRNA half-life. READ MORE

  4. 2. Lysogenic or lytic cycle of bacteriophage P2 : a transcriptional switch

    Author : Shamol Saha; Uppsala universitet; []
    Keywords : NATURAL SCIENCES; NATURVETENSKAP;

    Abstract : .... READ MORE

  5. 3. Nuclear receptor corepressor N-CoR : role in transcriptional repression

    Author : Kristina Loinder; Mats Söderström; Eckardt Treuter; Linköpings universitet; []
    Keywords : MEDICINE; MEDICIN;

    Abstract : The human body consists of a multitude of cells of varying appearance and function. With a few exceptions they are genetically identical, and the key to their divergence lies in their different specific patterns of gene expression. READ MORE

  6. 4. Exploring the transcriptional space

    Author : Joseph Bergenstråhle; Joakim Lundeberg; Jay W. Shin; KTH; []
    Keywords : Transcriptomics Spatial; Bioteknologi; Biotechnology;

    Abstract : Transcriptomics promises biological insight into gene regulation, cell diversity, and mechanistic understanding of dysfunction. Driven by technological advancements in sequencing technologies, the field has witnessed an exponential growth in data output. Not only has the amount of raw data increased tremendously but it’s granularity as well. READ MORE

  7. 5. An analytical framework for studying transcriptional regulation

    Author : Christoph Sebastian Börlin; Chalmers tekniska högskola; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; transcription factor; ChIP-exo; S. cerevisiae; transcriptional regulation;

    Abstract : The state and behavior of any living cell is controlled by a complex interplay of different regulatory processes, with the regulation of transcription playing a major role. When a cell adapts to a new environment it often does that by modulating gene transcript levels, mainly through changes in transcription factor binding events. READ MORE