Search for dissertations about: "Transcriptomics"

Showing result 16 - 20 of 171 swedish dissertations containing the word Transcriptomics.

  2. 16. Deradicalising Giardiasis Treatment

    Author : Sascha Krakovka; Staffan Svärd; Jon Jerlström-Hultqvist; Norbert Müller; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Giardia; encystation; antibiotic resistance; metronidazole; transcriptomics; proteomics; thymidine kinase;

    Abstract : Giardia intestinalis is a unicellular parasite causing the disease giardiasis. This disease is mostly prevalent in low resource settings, mandating low-cost treatment options. READ MORE

  4. 17. An insight towards food-related microbial sets through metabolic modelling and functional analysis

    Author : Simonas Marcisauskas; Chalmers tekniska högskola; []
    Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; NATURVETENSKAP; NATURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; RAVEN; gut; systems biology; comparative genomics; Kluyveromyces marxianus; bile acids; genome-scale metabolic model; next-generation sequencing; transcriptomics; thermotolerance;

    Abstract : The dietary food digestion depends on the human gastrointestinal tract, where host cells and gut microbes mutually interact. This interplay may also mediate host metabolism, as shown by microbial-derived secondary bile acids, needed for receptor signalling. Microbes are also crucial in the production of fermented foods, such as wine and dairy. READ MORE

  5. 18. Molecular biology of barnacle Balanus improvisus settlement

    Author : Anna Abramova; Göteborgs universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; barnacles; settlement; transcriptomics; ecdysone cascade; chemosensory receptors; waterborne pheromones;

    Abstract : The aim of this thesis was to investigate molecular mechanisms of various aspects of barnacle settlement, using the acorn barnacle Balanus improvisus. This barnacle is a common fouling species and a model organism for studies in settlement biology, in particular in relation to antifouling research. READ MORE

  6. 19. Pan-cancer study of transcriptional responses to oncogenic somatic mutations

    Author : Arghavan Ashouri; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Cancer; Driver mutations; Genomics; Transcriptomics; lncRNAs; NRF2; ALK;

    Abstract : Cancer cells typically carry acquired somatic mutations in key cancer driver genes, which can be identified on the basis of recurrence in cancer cohorts. Such mutations may cause aberrant protein activity and altered gene expression in the nucleus, driving the cell toward a cancerous phenotype. READ MORE

  7. 20. Data integration and visualization in type 2 diabetes research and care: From biological mechanisms to precision medicine

    Author : Olof Asplund; diabetes och endokrinologi Genomik; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Type 2 diabetes T2D ; human pancreatic islets; human skeletal muscle; transcriptomics; genomics; phenomics; ANDIS; diabetes; diabetics;

    Abstract : Background. Type 2 diabetes (T2D) is a complex heterogeneous disorder affecting multiple organs. Gene expression studies in organs central to T2D, such as pancreatic islets and skeletal muscle will help elucidate and disentangle molecular mechanisms underlying T2D. READ MORE