Search for dissertations about: "Transcriptomics"

Showing result 6 - 10 of 172 swedish dissertations containing the word Transcriptomics.

  2. 6. The Spatial Context – through the lens of method development

    Author : Linda Kvastad; Joakim Lundeberg; Lars Feuk; KTH; []
    Keywords : RNA; RNA-sequencing; transcriptomics; spatial transcriptomics; single cells; pediatric brain tumors; Spatial RIN; Bioteknologi; Biotechnology;

    Abstract : In the present moment of time, we find ourselves in a period where the advancement of genomic tools is progressing at a fast pace. Of particular interest for this thesis is the study of gene activity. READ MORE

  4. 7. Computational methods for analysis and visualization of spatially resolved transcriptomes

    Author : Jose Fernandez Navarro; Joakim Lundeberg; Martin Hemberg; KTH; []
    Keywords : RNA; RNA-seq; single cell; scRNA-seq; transcriptomics; spatial transcriptomics; brain; 3D; Alzheimer’s disease; Bioteknologi; Biotechnology;

    Abstract : Characterizing the expression level of genes (transcriptome) in cells and tis- sues is essential for understanding the biological processes of multicellular or- ganisms. RNA sequencing (RNA-seq) has gained traction in the last decade as a powerful tool that provides an accurate quantitative representation of the transcriptome in tissues. READ MORE

  5. 8. Systems Biology of Glucose Sensing and Repression in Aspergillus niger: Lessons from Genomics and Transcriptomics

    Author : Margarita Salazar Pena; Chalmers tekniska högskola; []
    Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; A. niger; Aspergillus spp.; Transcription Factors; Regulation; Metabolism; Transcriptomics;

    Abstract : Aspergillus comprises a genus of multicellular eukaryotic microorganisms containing close to 200 different species. Among them, the filamentous fungus Aspergillus niger exhibits great diversity in its phenotype and it is found, both in marine and terrestrial habitats. A. niger produces many metabolites that are valuable commodities, e. READ MORE

  6. 9. Development and application of spatial transcriptomics methods

    Author : Zaneta Andrusivova; Joakim Lundeberg; Jay W. Shin; KTH; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; RNA; Spatial Transcriptomics; RNA sequencing; Biotechnology; Bioteknologi;

    Abstract : Transcriptomics is one of the pivotal fields in molecular biology, enabling comprehensive analysis of gene expression patterns. Recent advancements in the biotechnology field have transformed the transcriptomics research, providing insights into the complexity of cellular processes in a greater detail. READ MORE

  7. 10. Computational Methods for Image-Based Spatial Transcriptomics

    Author : Axel Andersson; Carolina Wählby; Anna Klemm; Filip Malmberg; Karl Åström; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Spatial omics; Spatial transcriptomics; Spatial biology; In Situ Sequencing; Visualization; Spatial statistics; Fluorescence microscopy; Computerized Image Processing; Datoriserad bildbehandling;

    Abstract : Why does cancer develop, spread, grow, and lead to mortality? To answer these questions, one must study the fundamental building blocks of all living organisms — cells. Like a well-calibrated manufacturing unit, cells follow precise instructions by gene expression to initiate the synthesis of proteins, the workforces that drive all living biochemical processes. READ MORE