Search for dissertations about: "Transdermal formulation"

Found 4 swedish dissertations containing the words Transdermal formulation.

  2. 1. Ceramic Materials for Administration of Potent Drugs

    Author : Bing Cai; Susanne Bredenberg; Håkan Engqvist; Wei Xia; Miguel Manzano García; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Tamper-resistance; Oral formulation; Transdermal formulation; Biomaterials; Microneedles;

    Abstract : This thesis aimed to investigate and document the potential of applying ceramics in two specific drug delivery applications: tamper-resistant opioid formulations and transdermal enhancement protrusions.Geopolymers were developed into the matrix for a tamper-resistant formulation, aiming to protect drug substances from non-medical abuse. READ MORE

  4. 2. Electrolyte structures and ionization conditions for iontophoretic drug formulation of local anesthetics

    Author : Kiomars Karami; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pharmaceutical chemistry; Farmaceutisk kemi; Pharmaceutical chemistry; Farmaceutisk kemi; Physical and Inorganic Pharmaceutical Chemistry; fysikalisk och oorganisk farmaceutisk kemi;

    Abstract : Iontophoresis is a modern method of drug delivery by which charged bioactive molecules (drugs) are transferred from an electrolytic reservoir into and through a tissue, normally skin, by means of a weak electric current. The drug is placed in a conductive medium, usually an aqueous solution or a hydrogel, between the "active" electrode and the skin. READ MORE

  5. 3. New insights in contact allergy and drug delivery. A study of formulation effects and hapten targets in skin using two-photon fluorescence microscopy

    Author : Carl Simonsson; Göteborgs universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; contact allergy; cubic phases; cutaneous absorption; bromobimane; isothiocyanate; lipid vesicles; nano; pilosebaceous unit; ; two-photon microscopy;

    Abstract : The skin is a remarkable barrier, protecting us from invasion of e.g. harmful microorganisms and UV-radiation. However, the skin is not adopted to resist repeated exposure to the multitude of xenobiotics introduced into modern society. READ MORE

  6. 4. Factors of impotance for women's health at midlife with special emphasis on effect by sex steroids

    Author : Cairu Li; Kardiovaskulär forskning - epidemiologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; andrologi; reproduktion; reproduction; sexuality; Obstetrik; gynekologi; sexualitet; andrology; gynaecology; Obstetrics; lipids; carbohydrate metabolism; norethisterone acetate; estradiol; HRT; symptomatology; Menopause; midlife women;

    Abstract : Menopause is not a disease, but may bring about a wide range of health complaints and increase some risks of illnesses. The aim of this study was to evaluate the general health status and influences of background factors on symptomatology among a cohort of Swedish women aged 50-64 years, with specific emphasis on the effects of hormone replacement therapy (HRT) by investigating a profile of HRT use, long-term effects of HRT by different tapes and routes of administration as well as clinical and metabolic changes by use of low dose HRT. READ MORE