Search for dissertations about: "Transepithelial electrical resistance"

Showing result 1 - 5 of 11 swedish dissertations containing the words Transepithelial electrical resistance.

  2. 1. Surfactants based on natural products - enzymatic synthesis and functional characterization

    Author : Fredrik Viklund; KTH; []
    Keywords : Enzymatic synthesis; Surfactants; Antioxidants; Ascorbyl oleate; Polyethylene glycol PEG esters; Hemolysis; Transepithelial electrical resistance; Ionic liquids; Candida antarctica lipase B;

    Abstract : Surfactants are molecules that contain a water-soluble and afat-soluble part. They have important functions in productssuch as detergents, cosmetics, pharmaceuticals and foods aswell as in many industrial processes. Surfactants are used onvery large scale, which makes it important to decrease theirimpact on the environment. READ MORE

  4. 2. On the Regulation of the Epithelial Paracellular Permeability

    Author : Pia Nybom; Janove Sehlin; Linköpings universitet; []
    Keywords : MEDICINE; MEDICIN;

    Abstract : The epithelia of for instance the small intestine(s) plays a crucial role in the vectorial transport of nutrients and other solutes from the lumen to underlying body fluids, i.e. blood and lymph. READ MORE

  5. 3. The mucus layer and other barriers to intestinal drug absorption

    Author : Agneta Wikman Larhed; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pharmacy; FARMACI; PHARMACY; FARMACI; galenisk farmaci; Pharmaceutics;

    Abstract : The extraepithelial mucus layer acts as a barrier to the absorption and diffusion of drugs. Three in vitro models have been used for studies of this and other intestinal barriers to drug transport. A drug absorption model based on monolayers of the mucus-producing human intestinal goblet HT29-H cell line was developed. READ MORE

  6. 4. Epithelial barrier dysfunction in ileal Crohn's disease

    Author : Johan Dabrosin-Söderholm; Svante Nordgren; Linköpings universitet; []
    Keywords : acetylsalicylic add; confocal microscopy; Crohn s disease; cytoskeleton; electron microscopy; genetics; human; ileum; inflammatory bowel disease; intestinal absorption; intestinal mucosa; macromolecules; mitochondria; ovalbumin; permeability; sodium caprate; tight junctions; transcytosis; uncoupling agents; Ussing chamber; MEDICINE; MEDICIN;

    Abstract : The study aimed at investigating the intestinal barrier in Crohn's disease, with special reference to epithelial responses to luminal stimuli, and to permeation of proteins.Ileal mucosa from patients undergoing intestinal resection was studied in vitro in Ussing chambers. READ MORE

  7. 5. The Horizontal Ussing Chamber Method in Studies of Nasal Drug Delivery : Method Development and Applications Using Different Formulations

    Author : Karin Östh; Anna-Lena Ungell; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pharmacy; FARMACI; PHARMACY; FARMACI; galenisk farmaci; Pharmaceutics;

    Abstract : The results from this thesis leads to the following conclusions; HUM is a useful tool that fills a gap in the in vitro methods previously available to study nasal drug delivery. Using HUM, the pig respiratory nasal mucosa can obtain acceptable viability and retain it longer than the period of time needed for a transport experiment. READ MORE