Search for dissertations about: "Transgenic mouse"
Showing result 1 - 5 of 285 swedish dissertations containing the words Transgenic mouse.
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1. Molecular characterization of prostate hyperplasia in prolactin transgenic mice
Abstract : Benign prostatic hyperplasia (BPH) and prostate cancer are age-related diseases, affecting a majority of elderly men in the western world, and are known to be influenced by several different hormones, including sex hormones. Although the hormone prolactin (PRL) is well known to exert trophic effects on prostate cells, its involvement in the pathophysiology is still poorly characterized. READ MORE
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2. Of mice and men : SOD1 associated human amyotrophic lateral sclerosis and transgenic mouse models
Abstract : Amyotrophic lateral sclerosis, ALS, is a progressive fatal neurodegenerative disorder affecting motor neurones in motor cortex, brain stem and spinal cord. This inevitably leads to paralysis, respiratory failure and death. READ MORE
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3. Studies of Spinal Motor Control Networks in Genetically Modified Mouse Models
Abstract : Spinal neurons are important in several aspects motor control. For example, the neurons essential for locomotor movements reside in the ventral spinal cord. In this thesis, different motor control functions are being related to neuronal populations defined by their common expression of a gene. READ MORE
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4. Feedback Enhancement of Antibody Responses via Complement and Fc Receptors
Abstract : IgG, IgM and IgE in complex with antigen have the capacity to regulate specific immune responses. In this investigation, the role of Fc receptors for IgG (FcγRI, FcγRII and FcγRIII) and complement receptors 1 and 2 (CR1/2) for antibody-mediated enhancement of antibody responses are investigated. READ MORE
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5. Fcγ Receptors in the Immune Response
Abstract : Circulating immune complexes play an important role in the modulation of antibody responses and in the pathogenesis of immune diseases. This thesis deals with the in vivo regulatory properties of antibodies and their specific Fc receptors. READ MORE