Search for dissertations about: "Trastuzumab in treatment for breast cancer"
Showing result 1 - 5 of 9 swedish dissertations containing the words Trastuzumab in treatment for breast cancer.
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1. Meta-analysis of randomized clinical evidence of chemotherapy, radiotherapy and endocrine therapy in breast cancer
Abstract : Breast cancer is the most frequently diagnosed cancer and the leading cause of cancer death in females worldwide. Despite the growing body of randomized controlled trials (RCTs) regarding the use of various treatment strategies (chemotherapy, endocrine therapy, radiotherapy) in breast cancer, the efficacy of some strategies remains unclear and questionable. READ MORE
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2. The Prognostic and Treatment Predictive Value of Proliferation and TIMP-1 in Breast Cancer
Abstract : Breast cancer is the most common tumour form and the second leading cause of death in solid tumours in women in the Western world. Despite improvements in the treatment, a considerable number of patients will relapse and die from their breast cancer. READ MORE
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3. Pharmacometric Models for Antibody Drug Conjugates and Taxanes in HER2+ and HER2- Breast Cancer
Abstract : In oncology, there is a need to optimize drug treatment for efficient eradication of tumors, minimization of adverse effects (AEs), and prolonging patient survival. Pharmacometric models can be developed to streamline information between drug development phases, describe and quantify response to treatment, and determine dose regimens that balance toxicity and efficacy. READ MORE
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4. Studies of targeted therapy in breast cancer using trastuzumab : HER2 testing and trastuzumab treatment, clinical and economic evaluation
Abstract : The incidence in breast cancer has more than tripled in Sweden since the 1960-ies. During the same time period the 5-year survival rate has increase from around 65% to almost 90%. The survival increase is mainly related to medical treatments (endocrine treatments, chemotherapy in different combinations), radiotherapy and breast cancer screening. READ MORE
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5. Radiolabeled HER-2 Binding Affibody Molecules for Tumor Targeting : Preclinical Studies
Abstract : Conventional cancer treatment based on radiotherapy or chemotherapy affects all dividing cells. By directing the therapy specifically to the tumor cells, normal cells can be spared. Tumor targeting molecules carrying a cytotoxic moiety is then an attractive approach. READ MORE