Search for dissertations about: "Triapine"
Found 2 swedish dissertations containing the word Triapine.
-
1. Activation and inhibition of diiron and iron-manganese ribonucleotide reductases
Abstract : Ribonucleotide reductase (RNR) catalyses the reduction of ribonucleotides to deoxyribonucleotides. In conventional class I RNRs the active site is located in the R1 subunit, and the R2 subunit contains a diiron cofactor and a stable tyrosyl radical essential for activity. READ MORE
-
2. Genetic determinants of lung cancer and their application toward therapeutics. The role of ZFP148 transcription factor and anaplastic lymphoma kinase (ALK) fusion proteins in non-small cell lung cancer
Abstract : Lung cancer causes severe morbidity and mortality in millions of patients globally each year. Anaplastic lymphoma kinase (ALK) mutations facilitate neoplastic growth of lung cancer in adults and neuroblastoma in pediatric patients. READ MORE