Search for dissertations about: "Trypanosoma cruzi"

Showing result 16 - 19 of 19 swedish dissertations containing the words Trypanosoma cruzi.

  1. 16. Structural and Functional Studies of Chagasin, a Parasite Protease Inhibitor

    Author : Anna Ljunggren; Avdelningen för klinisk kemi och farmakologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Abstract : The cysteine proteases are enzymes found in every kingdom of life. Clan CA is the largest of the cysteine protease clans, with members all displaying a Cys/His/Asn(Asp) catalytic triad responsible for hydrolysing the peptide bond within the substrate. READ MORE

  2. 17. Solving repeat problems in shotgun sequencing

    Author : Erik Arner; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Shotgun sequencing; repeated DNA; genomics; whole genome shotgun; hierarchical shotgun; mate pairs; DNP; bioinformatics;

    Abstract : Shotgun sequencing is the most powerful strategy for large scale sequencing. Two main approaches exist: clone-by-clone and whole genome shotgun (WGS). In the clone-by-clone strategy, overlapping clones are amplified and then sheared in a random fashion. READ MORE

  3. 18. Studies of the recognition and activation of natural killer cells

    Author : Clas Une; Karolinska Institutet; Karolinska Institutet; []
    Keywords : NK cells; activation; cytotoxicity; IFN-[gamma] IFN-[alpha] [beta]; IL-12; G-PI; MHC class I;

    Abstract : Natural killer (NK) cells mediate part of the innate immune response that impedes the spread of invading microorganisms and shapes the downstream adaptive immune response. NK cells spontaneously kill tumor cells and other cells upon contact. Killing requires engagement of germline encoded receptors that mediate positive and negative signals. READ MORE

  4. 19. Heat shock proteins as vaccine adjuvants

    Author : Khaleda Rahman Qazi; Carmen Fernández; Qijun Chen; Stockholms universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Heat shock protein; vaccine; adjuvant; BCG; Immunology; Immunologi;

    Abstract : New efficient vaccines against infectious diseases are in demand. Some important factors impeding the vaccine development are the poor immunogenicity and the MHC restriction of the immune responses to a number of antigens. READ MORE