Search for dissertations about: "Trypanosoma"

Showing result 6 - 10 of 39 swedish dissertations containing the word Trypanosoma.

  2. 6. Nucleotide Metabolism of the Human Pathogen Trypanosoma brucei

    Author : Anders Hofer; Lars Thelander; Umeå universitet; []
    Keywords : ;

    Abstract : .... READ MORE

  4. 7. Mapping the genome and characterization of an acetyltransferase of Trypanosoma cruzi

    Author : Stephen O Ochaya; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Trypanosoma cruzi; Chagas´disease; karyotyping; genomic; acetyltransferase;

    Abstract : Trypanosoma cruzi (T.cruzi) is a flagellate protozoan parasite that causes Chagas' disease and is most common in Latin American countries. The disease currently infects over 13 million persons and about 100 million more are at risk. Despite basic research for many years, there is neither a vaccine nor useful drugs available to combat the disease. READ MORE

  5. 8. Detection and characterization of novel proteins in Trypanosoma cruzi

    Author : Marcela Ferella; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Trypanosoma cruzi is a flagellated protozoan parasite. It infects a wide range of mammals, including humans. Human T. cruzi infections are endemic to South and Central America. READ MORE

  6. 9. Gene Regulation and Epigenetic Mechanisms in the Parasite Trypanosoma cruzi

    Author : Patricia Respuela; Lena Åslund; George A.M. Cross; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Molecular biology; Molekylärbiologi; Molecular Biology; Molekylärbiologi;

    Abstract : Trypanosomes are unicellular protozoan parasites responsible for several human diseases that affect millions of people and cause thousands of casualties every year. They also represent a primitive eukaryotic model system harboring unique processes and basic regulatory mechanisms such as RNA-editing, polycistronic transcription and trans-splicing, first described in these organisms. READ MORE

  7. 10. DNA precursor biosynthesis-allosteric regulation and medical applications

    Author : Reza Rofougaran; Anders Hofer; Thomas Borén; Staffan Eriksson; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Biochemistry; DNA biosynthesis; ribonucleotide reductase; allosteric regulation; Trypanosoma brucei; adenosine kinase; nucleoside analogs; mitochondrial DNA; TWINKLE; Biokemi; medicinsk biokemi; Medical Biochemistry;

    Abstract : Ribonucleotide reductase (RNR) is a key enzyme for de novo dNTP biosynthesis. We have studied nucleotide-dependent oligomerization of the allosterically regulated mammalian RNR using a mass spectrometry–related technique called Gas-phase Electrophoretic Mobility Macromolecule Analysis (GEMMA). READ MORE