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Showing result 1 - 5 of 13 swedish dissertations matching the above criteria.

  2. 1. Modeling of dose and sensitivity heterogeneities in radiation therapy

    Author : Kristin Wiklund; Bengt K. Lind; Iuliana Toma-Dasu; Marco Zaider; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Monte Carlo simulations; Tumor control probability; Modeling; Beam characterization; Medical Radiation Physics; medicinsk strålningsfysik;

    Abstract : The increased interest in the use of light ion therapy is due to the high dose conformity to the target and the dense energy deposition along the tracks resulting in increased relative biological effectiveness compared to conventional radiation therapy. In spite of the good clinical experience, fundamental research on the characteristics of the ion beams is still needed in order to be able to fully explore their use. READ MORE

  4. 2. Tumor radiosensitivity and proliferation as parameters for optimizing radiotherapy

    Author : Mattias Hedman; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Radiotherapy is a widely used method to treat malignant tumors. However, the sensitivity to the treatment varies between tumors, and local tumor control is not always achieved. The balance between treatment success and the side effects of the treatment affords important information for developing treatment schedules at patient population level. READ MORE

  5. 3. Nasopharyngeal carcinoma: past, present and future directions

    Author : Zahra Taheri-Kadkhoda; Göteborgs universitet; []
    Keywords : Nasopharyngeal carcinoma; radiotherapy; side effects; 3DCRT; Intracavitary brachytherapy; IMRT; IMPT; LMP1; EGFR.; radiotherapy; side effects; 3DCRT; Intracavitary brachytherapy; IMRT; IMPT; LMP1; EGFR;

    Abstract : Nasopharyngeal carcinoma (NPC) is a rare disease in Sweden. The purpose of this thesis was to investigate the clinicopathological manifestations of the disease and its treatment outcomes in a cohort of Swedish NPC patients to identify key features for future improvements in patient care. READ MORE

  6. 4. Dose painting : Can radiotherapy be improved with image driven dose-responses derived from retrospective radiotherapy data?

    Author : Eric Grönlund; Anders Ahnesjö; Silvia Johansson; Daniela Thorwarth; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Radiotherapy; functional imaging; dose painting; dose painting by numbers; robust optimization; Medicinsk radiofysik; Medical Radiophysics;

    Abstract : The main aim of curative radiotherapy for cancer is to prescribe and deliver doses that eradicate the tumor and spare the normal healthy tissues. Radiotherapy is commonly performed by delivering a homogeneous radiation dose to the tumor. READ MORE

  7. 5. Tools for the Advancement of Radiopharmaceutical Therapy

    Author : Emma Mellhammar; Forskningsgruppen för Systemisk strålterapi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Radiopharmaceutical therapy; Nuclear medicine; Monte Carlo simulation; Intratherapeutic preclinical PET; Alpha particles; Beta Particles; radionuclides; Radiobiology; γ-H2AX; Dosimetry;

    Abstract : Radiopharmaceutical therapy is used to treat cancers and other diseases with radiolabeled pharmaceuticals. The treatment targets specific cells, and the emitted ionizing radiation cause cytotoxic damage. Dosimetry is performed to estimate the absorbed dose from the energy deposited in the body. READ MORE