Search for dissertations about: "Tumor escape"
Showing result 1 - 5 of 52 swedish dissertations containing the words Tumor escape.
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1. Mechanisms for immune escape in epithelial ovarian cancer
Abstract : Tumors develop mechanisms to subvert the immune system, constituting immune escape. Epithelial ovarian cancer (EOC), the deadliest of all gynecological malignancies, uses a variety of mechanisms to undermine immune surveillance, aiding its establishment and metastatic spreading. READ MORE
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2. Therapeutic Cancer Vaccines Targeting Molecules Associated with Tumor Angiogenesis
Abstract : Induction of an endogenous antibody response by therapeutic vaccination could provide an alternative to cost-intensive monoclonal antibody-based treatments for cancer. Since the target of a cancer vaccine will most likely be a self-antigen, self-tolerance of the immune system must be circumvented. READ MORE
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3. Immune modulation in serous epithelial ovarian cancer : focus on the role of tumor-derived exosomes
Abstract : Serous epithelial ovarian cancer (EOC) is a potent suppressor of the immune defense. Here, we studied interactions between EOC and the immune system that lead to escape from tumor immune surveillance. READ MORE
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4. Immunological recognition and tumor escape mechanisms of ovarian carcinoma
Abstract : Ovarian carcinoma is a leading cause of cancer mortality and there is an urgent need for new and better therapeutic modalities that result in improved long-term outcome for this severe malignancy. One promising treatment modality for patients suffering from ovarian carcinoma is immunotherapy. READ MORE
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5. Mechanisms of immune escape : implications for immunotherapy against cancer
Abstract : Tumor cells can be recognized and killed by cytotoxic T cells specific for certain tumor antigens. Immune mediated selection pressure along with genetic instability of tumor cells result in a growth advantage of tumor cells that acquire a less immunogenic phenotype. READ MORE