Search for dissertations about: "Tumor immunology"
Showing result 6 - 10 of 111 swedish dissertations containing the words Tumor immunology.
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6. Transforming Growth Factor-b, Regulatory functions on normal lymphocytes and tumor outgrowth Regulatory functions on normal lymphocytes and tumor outgrowth
Abstract : Transforming growth factor-beta (TGF-b) is a well-characterised growth regulatory factor, which acts on most cell types. This thesis has focused on the regulatory roles of TGF-b on normal lymphocytes. One interesting finding is that TGF-b acts both costimulatory and inhibitory on T-lymphocytes. READ MORE
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7. Apoptosis in tumor immunity and immune evasion
Abstract : .... READ MORE
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8. Immunological analysis of the human tumor cell surface : characterization of polypeptides associated with urinary bladder carcinoma
Abstract : Tumors express antigens characteristic of their malignant phenotype, a fact that has become exploited for the diagnosis of certain types of cancer. As these tumor-associated antigens (TAA) may also provide Information on the molecular mechanisms of tumorogenesls as well as constituting the basis for immunotherapeutlc approaches, much Interest has been focused on the Identification and characterization of TAAs. READ MORE
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9. Vascular targeting for enhanced cancer immunotherapy
Abstract : Induced angiogenesis and chronic inflammation are major components of tumor immunosuppression. The scope of this thesis is to understand the role of the vasculature in anti-tumor immunity and thereby to improve cancer immunotherapy. READ MORE
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10. CD19-targeting CAR T Cells for Treatment of B Cell Malignancies : From Bench to Bedside
Abstract : Immunotherapy for cancer is a young research field progressing at high speed. The first chimera of an antibody and a signaling chain was designed by Zelig Eshhar and was later further developed to enhance existing T cell therapy by combining a single-chain fragment of an antibody with the CD3 zeta chain of the TCR complex. READ MORE