Search for dissertations about: "Tumor-Antigens"

Showing result 16 - 20 of 21 swedish dissertations containing the word Tumor-Antigens.

  2. 16. Strengthening the pillars of cancer immunotherapy

    Author : Maarten Alexander Ligtenberg; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : The treatment of disease in cancer patients by harnessing the potent mechanisms that exist within the immune system is not a novel approach, and has been first attempted more than a century ago. During the major part of this century cancer immunotherapy has been relegated to the periphery of standard care for patients. READ MORE

  4. 17. Delivery of DNA vaccines against cancer

    Author : Anna-Karin Roos; Karolinska Institutet; Karolinska Institutet; []
    Keywords : DNA vaccine; prostate-specific antigen; immunotherapy; prostate cancer; electroporation;

    Abstract : DNA vaccines against cancer have shown promising results in animal models. Efficient antigenspecific T cell responses and tumor protection have been demonstrated after vaccination with DNA encoding tumor antigens in mice. READ MORE

  5. 18. Mechanisms of immune escape : implications for immunotherapy against cancer

    Author : Karl-Johan Malmberg; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Tumor Immunology; Immune escape; NK receptors; T lymphocytes; Oxidative stress; Vitamin E;

    Abstract : Tumor cells can be recognized and killed by cytotoxic T cells specific for certain tumor antigens. Immune mediated selection pressure along with genetic instability of tumor cells result in a growth advantage of tumor cells that acquire a less immunogenic phenotype. READ MORE

  6. 19. Studies on polyomavirus virus-like particles : as vaccines and vectors for immune and gene therapy

    Author : Karin Tegerstedt; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Polyomavirus; virus-like particles; immunotherapy; Her2 and dendritic cells;

    Abstract : Virus-like particles (VLPs) are similar to natural virus particles except that they lack viral genes. They have a similar cellular uptake to the natural virus from which they are derived but are non-infectious and can therefore not reproduce themselves. READ MORE

  7. 20. Optimizing experimental radioimmunotherapy : investigating the different mechanisms behind radiation induced cell deaths

    Author : Theres Lindgren; David Eriksson; Torgny Stigbrand; Bo Stenerlöw; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; mitotic catastrophe; senescence; cell cycle checkpoint; apoptosis; radiation; gene expression; p53; immunologi; Immunology; radiofysik; radiation physics;

    Abstract : Background. Radiation therapy is an important treatment regimen for malignant disease. Radiation therapy uses ionizing radiation to induce DNA damage in tumor cells in order to kill them. READ MORE