Search for dissertations about: "Tumors"

Showing result 21 - 25 of 1337 swedish dissertations containing the word Tumors.

  1. 21. Accurate description of heterogeneous tumors for biologically optimized radiation therapy

    Author : Johan Nilsson; Bengt Lind; Anders Brahme; Margareta Edgren; Søren Bentzen; Stockholms universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; heterogeneous tumors; radiation therapy; biological optimization; tumor hypoxia; effective radiation sensitivity; effective radiation resistance; Radiation biology; Strålningsbiologi;

    Abstract : In this thesis, a model of tissue oxygenation is presented, that takes into account the heterogeneous nature of tumor vasculature. Even though the model is rather simple, the resulting oxygen distributions agree very well with clinically observed oxygen distributions for most tumors and healthy normal tissues. READ MORE

  2. 22. Sarcoma of the female genital tract : Histopathology, DNA cytometry, p53 and mdm-2 analysis related to prognosis

    Author : René Blom; Ernst Simonsen; Henric Malmström; Olle Stål; Anders Jakobsen; Linköpings universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Sarcoma; female genital tract; tumors; MMMT; Oncology; Onkologi;

    Abstract : Sarcomas of the female genital tract are rare tumors and account for less than 5% of gynecologic malignancies. Traditionally, gynecologic sarcomas have been divided into different tumor types according to their histopathological features. READ MORE

  3. 23. Immunomodulatory Therapy of Solid Tumors : With a Focus on Monoclonal Antibodies

    Author : Linda Sandin; Thomas Tötterman; Mangsbo Sara; Fredrik Eriksson; Loskog Angelica; Ola Winqvist; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; in situ checkpoint blockade; antibody-mediated tumor immunotherapy; CTLA-4; CD40; monoclonal antibodies; experimental animal model; Fc gamma receptor; Medical Science; Medicinsk vetenskap;

    Abstract : Cancer, historically considered a genetic disease, is currently acknowledged to affect the whole body. Our immune system is one key player that can elicit a response against malignant cells but can also promote tumorigenesis. Tumors avoid immune recognition by creating a suppressive microenvironment and inducing tolerance. READ MORE

  4. 24. Metastatic Mechanisms in Malignant Tumors

    Author : Linda Bojmar; Per Sandström; Olle Stål; Marie Larsson; Ingemar Ernberg; Linköpings universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Abstract : The ultimate cause of cancer related deaths is metastasis. This thesis is about three of the main human cancers; breast, colorectal and pancreatic cancer, that together account for more than 25% of the cancer-related deaths worldwide. READ MORE

  5. 25. Current Medical Treatment of Endocrine Pancreatic Tumors and Future Aspects

    Author : Marie-Louise Fjällskog; Morten Vatn; Uppsala universitet; []
    Keywords : Medical sciences; pancreatic tumors; somatostatin analogs; cisplatin; etoposide; somatostatin receptors; immunohistochemistry; tyrosine kinase receptors; platelet-derived growth factors receptors PDGFRs ; c-kit; epidermal growth factor receptor EGFR ; MEDICIN OCH VÅRD; alfa-interferon; MEDICINE; MEDICIN; Medicine; medicin;

    Abstract : We treated 16 patients with somatostatin analogs combined with α-interferon and achieved a biochemical and/or radiological response in 56% (median duration 22 months). We consider this treatment a good alternative for patients who fail during chemotherapy or who do not want to/cannot receive cytotoxic drugs. READ MORE