Search for dissertations about: "TxA2"

Showing result 1 - 5 of 7 swedish dissertations containing the word TxA2.

  1. 1. Endothelial cell seeding and the thrombogenicity of vascular grafts

    University dissertation from Dept of Surgery, Centralsjukhuset, 65185 Karlstad. Karlstad

    Author : Norman Jensen; [1996]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Surgery; humans.; sheep; Iodine-125; Technetium-99m; Indium-111; TxA2; PGI2; fibrinogen; leukocyte; platelet; cell seeding; Blood vessel prosthesis; endothelium; orthopaedics; traumatology; Kirurgi; ortopedi; traumatologi; Immunology; serology; transplantation; Immunologi; serologi;

    Abstract : ABSTRACT In humans, synthetic vascular grafts heal with a limited ingrowth of endothelium. This fact might be responsible for inferior performance of synthetic grafts compared with native artery.Endothelial cells can be autotransplanted (seeded) into the graft in an effort to improve graft function. READ MORE

  2. 2. Studies on antibodies against phospholipids

    University dissertation from Stockholm : Karolinska Institutet, false

    Author : Leopold Årfors; Karolinska Institutet.; Karolinska Institutet.; [1997]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Antiphospholipid syndrome; anticardiolipin antibodies; lupus anticoagulants; platelets; platelet activation; complement activation; endothelial cells; thromboxane; prostacyclin; acetylsalicylic acid.;

    Abstract : The main clinical features of the antiphospholipid syndrome (APLS) are arterial andvenous thrombosis, repeated spontaneous abortions and thrombocytopenia. Diagnosedconcomitant with an underlying disease the designation is secondary APLS; otherwiseprimary APLS. READ MORE

  3. 3. Effects of high glucose on platelet activation

    University dissertation from Stockholm : Karolinska Institutet, Department of Medicine

    Author : Masoud Razmara; Karolinska Institutet.; Karolinska Institutet.; [2006]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Abstract : Diabetes mellitus (DM) is associated with increased cardiovascular mortality and morbidity, due to diabetic angiopathy. Hyperglycaemia is one of the factors that may cause platelet dysfunction in diabetic patients. This work investigated the mechanisms underlying hyperglycaemia-induced platelet hyperreactivity and its impact in diabetic patients. READ MORE

  4. 4. Pleiotropic Effects of HMG-CoA Reductase Inhibitors - studies in vitro and in vivo

    University dissertation from Stockholm : Karolinska Institutet, Dept of Laboratory Medicine

    Author : Cristine Skogastierna; Karolinska Institutet.; Karolinska Institutet.; [2012]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Abstract : Cardiovascular disease (CVD) is the prime cause of death in industrialized countries, resulting from the progression of atherosclerotic lesions. An increased level of plasma cholesterol, particularly within low-density lipoproteins, is a principle risk factor, but also elevated triglycerides and low levels of high-density lipoprotein cholesterol. READ MORE

  5. 5. Platelet dysfunction in diabetes mellitus : Impact of hyperglycemia and glycoprotein GPIIb/IIIa inhibition

    University dissertation from Stockholm : Karolinska Institutet, Department of Medicine

    Author : Masoud Razmara; Karolinska Institutet.; Karolinska Institutet.; [2009]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Abstract : Diabetes mellitus (DM) is associated with increased cardiovascular morbidity and mortality, due to diabetic angiopathy. Hyperglycemia is one of the factors that may cause platelet dysfunction in diabetic patients. This work investigated mechanisms underlying hyperglycemia-induced platelet dysfunction, and its impact in DM patients. READ MORE