Search for dissertations about: "Type I interferons"

Showing result 1 - 5 of 36 swedish dissertations containing the words Type I interferons.

  2. 1. Induction of type I interferons and viral immunity

    Author : Åsa Hidmark; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Virus-induced type I interferons (IFNα/β) are key mediators of innate immunity and important modulators of adaptive immunity. Early recognition of virus and induction of IFNα/β are important for limiting the spread of the virus. READ MORE

  4. 2. Induction of type I interferons and viral immunity

    Author : Åsa Hidmark; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Virus-induced type I interferons (IFNα/β) are key mediators of innate immunity and important modulators of adaptive immunity. Early recognition of virus and induction of IFNα/β are important for limiting the spread of the virus. READ MORE

  5. 3. Regulation of the germinal center response by T follicular helper cells and type I interferons

    Author : Madelene Dahlgren; Adaptivt immunförsvar; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Germinal Center; T follicular helper cell; type I interferon; dendritic cell; adjuvant; differentiation; IgG;

    Abstract : The protective effect of most currently available vaccines is dependent on high-affinity antibodies and long lived B cell memory, which develop within organized structures of secondary lymphoid organs called germinal centers (GCs). GC formation is supported by T follicular helper (Tfh) cells, a subset of CD4+ T cells that develop in parallel to other effector T cells and specifically localizes to B cell follicles. READ MORE

  6. 4. Mechanisms of type I interferons in autoimmunity and cancer

    Author : William A Nyberg; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Interferons (IFNs) were first described in the 1950’s and has since been characterized as potent inducers of pathogen defense mechanisms. Since then, researchers have uncovered a depth of mechanisms in the IFN system extending beyond immune modulation of pathogen defense. READ MORE

  7. 5. The Role of Maf Transcription Factors in Islet Inflammation and Βeta Cell Function

    Author : Tania Singh; Stamcellscentrum (SCC); []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Diabetes; T cells; pancreas; resident lymphocytes; autoimmunity; Insulin secretion; pancreas development; Type 1 and Type 2 diabetes; inflammation and leukocyte; Cytokines: immunology; Transcription Factor MAFs; Interferons;

    Abstract : Endocrine disorders that lead to a state of chronic high blood glucose levels are collectively referred to as diabetes. This metabolic disease is mainly categorized into type 1 (T1D) and type 2 diabetes (T2D). These diabetic forms originate from distinct triggering environmental, genetic, and altered mechanisms. READ MORE